BIOPEP-UWM: Report

ID 3175
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
LA

Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 202.2501 Monoisotopic mass 202.1313
EC50 :
0.00 µM



Bibliographic data:
Authors
Bella A. M., Erickson R. H. Jr., Kim Y. S.
Title
Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV:kinetic properties and substrate specifities of the purified enzyme.Arch.Biochem.Biophys. 218 (1), 156-162
Year Source
1982 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)C)CC(C)C

InChI=1S/C9H18N2O3/c1-5(2)4-7(10)8(12)11-6(3)9(13)14/h5-7H,4,10H2,1-3H3,(H,11,12)(H,13,14)/t6-,7-/m0/s1

InChIKey: HSQGMTRYSIHDAC-BQBZGAKWSA-N


Information concerning Dipeptidyl Peptidase IV (synonym: Dipeptidyl Aminopeptidase IV) (EC 3.4.14.5) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.003

Another reference concerning peptide:
Tulipano G., Sibilia V., Caroli A. M., Cocchi D., 2011, Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides, 32, 835-838


Activator of ubiquitin-mediated proteolysis according to the BIOPEP-UWM database of bioactive peptides (ID 4006); the EROP-Moscow database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BindingDB database, the BIOPEP-UWM database of bioactive peptides (ID 7585); the ChEMBL database; the PubChem database
Inhibitor of Bleomycin hydrolase (EC 3.4.22.40) (MEROPS ID: C01.084) according to the BRENDA database
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9499)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; the ChEMBL database; the PubChem database



Database reference:
ACToR: ID 21369-94-8

AHTPDB: ID 3224, 3308, 3513, 3569, 3595, 3828, 3852, 3973, 4437, 4534, 4672, 6571

BindingDB: ID 50407466

BioPepDB: ID biopep00725

BIOPEP-UWM database of bioactive peptides: ID 4006; 7585; 9499

BIOPEP-UWM database of sensory peptides and amino acids: ID 466

BRENDA: Ligand Leu-Ala

ChEBI: ID 73527

ChemBank: ID KBio3_002789; SPBio_001517; Spectrum2_001499; Spectrum3_001934

ChEMBL: ID CHEMBL541207

ChemIDplus: ID 007298842

ChemSpider: ID 73739

EROP-Moscow: ID E06287

J-GLOBAL: ID 200907083420885213

Nikkaji: ID J81.361C

PubChem: ID 81721

SATPDB: ID satpdb13367

SureChEMBL: ID SCHEMBL259116

ZINC: ID ZINC01569727