BIOPEP-UWM: Report

ID 3177
Name dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
sequence
AP
Function:
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
 
Number of residues
2
Activity code
dpp
Activity :
dipeptidyl peptidase IV inhibitor
Chemical mass 186.2078 Monoisotopic mass 186.1001
EC50 :
7950.00 µM


Bibliographic data:
Authors
Hatanaka T., Inoue Y., Arima J., Kumagai Y., Usuki H., Kawakami K., Kimura M., Mukaihara T.
Title
Production of dipeptidyl peptidase IV inhibitory peptides from defated rice bran. Food Chem., 134, 797-802
Year Source
2012 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N1[C@H](C(=O)O)CCC1)C

InChI=1S/C8H14N2O3/c1-5(9)7(11)10-4-2-3-6(10)8(12)13/h5-6H,2-4,9H2,1H3,(H,12,13)/t5-,6-/m0/s1

InChIKey=WPWUFUBLGADILS-WDSKDSINSA-N


First reference concerning peptide:
Bella A. M., Erickson R. H. Jr., Kim Y. S., Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV: kinetic properties and substrate specificities of the purified enzyme. Arch. Biochem. Biophys. 218 (1), 156-162 (1982)

Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP database of bioactive peptides (ID 7584); the BRENDA database; the ChEMBL database; the EROP-Moscow database; the PubChem database
Inhibitor of Tripeptidyl peptidase 2 (TPP 2) (EC 3.4.14.10) (MEROPS ID: S08.090) according to the BRENDA database; the ChEMBL database; the PubChem database
Inhibitor of Peptidylprolyl isomerase (EC 5.2.1.8) according to the BRENDA database


Database reference:
AHTPDB: ID 1079, 1118, 1504, 1507, 3223, 3420, 3468, 3554, 3607, 3706, 3792, 3890, 4060, 4438, 4498, 4685, 5135, 5639, 5675, 6162, 6570

BindingDB: ID 50020390

BIOPEP-UWM database of bioactive peptides: ID 7584

BRENDA: Ligand Ala-Pro

CAS: Registry No 13485-59-1

ChEBI: ID 73393

ChEMBL: ID CHEMBL414828

ChemIDplus: ID 013485591

ChemSpider: ID 75359

EChA: ID 236-795-8

EROP-Moscow: ID E09221

FDA SRS: ID C6G5K79L0O

FooDB: ID FDB098189

HMDB: ID HMDB0028695

J-GLOBAL: ID 200907099385554660

MeSH: Terms Ala-Pro; L-alanyl-L-proline

Metabolights: ID MTBLC73393, MTBLC155848

Metabolomics Workbench: ID 78670

Nikkaji: ID J81.627B

NMRShiftDB: ID 60021737

PlantPepDB: ID PPepDB_2898

PubChem: ID 83525

Rhea: ID 155848

SATPdb: ID satpdb17029

SureChEMBL: ID SCHEMBL152403

UNII: ID C6G5K79L0O

Wikidata: ID Q27140485

ZINC: ID ZINC04521128