BIOPEP-UWM: Report
| ID | 3182 |
| Name | dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) |
| sequence |
| Function: | |||
| Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) | |||
| Number of residues | 2 |
Activity code | dpp |
| Activity : | dipeptidyl peptidase IV inhibitor |
|||
| Chemical mass | 244.3296 | Monoisotopic mass | 244.1781 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Bella A. M., Erickson R. H. Jr., Kim Y. S. | |
| Title | |
| Rat intestinal brush border membrane dipeptidyl-aminopeptidase IV:kinetic properties and substrate specifities of the purified enzyme. Arch. Biochem. Biophys., 218 (1), 156-162 (1982) | |
| Year | Source |
| 1982 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)CC(C)C InChI=1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1 InChIKey: LCPYQJIKPJDLLB-UWVGGRQHSA-N Information concerning Dipeptidyl Peptidase IV (synonym: Dipeptidyl Aminopeptidase IV) (EC 3.4.14.5) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.003 Peptide found in whey protein hydrolysate: Morifuji M., Koga J., Kawanaka K., Higuchi M., 2009, Branched-chain amino acid-containing dipeptides, identified from whey protein hydrolysates, stimulate glucose uptake in L6 myotubes and isolated skeletal muscles. J. Nutr. Sci. Vitaminol., 55, 81-86 Peptide reveals also glucose uptake stimulating activity (BIOPEP ID 8326). Another reference concerning peptide: Tulipano G., Sibilia V., Caroli A. M., Cocchi D., 2011, Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides, 32, 835-838 Inhibitor of Cytosol alanyl aminopeptidase (EC 3.4.11.14) (MEROPS ID: M01.010) according to the BRENDA database Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database Inhibitor of Lactocepin (EC 3.4.21.96) (MEROP ID: S08.019) according to the BRENDA database Glucose uptake stimulating peptide according to the BIOPEP-UWM database of bioactive peptides Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 160); the ChEMBL database; the PubChem database |
| Database reference: |
| AHTPDB: ID 3853; 5405 BindingDB: ID 50188496 BIOPEP-UWM database of bioactive peptides: ID 8326 BIOPEP-UWM database of sensory peptides and amino acids: ID 160 BRENDA: Ligand Leu-Leu ChEBI: ID 73531 ChEMBL: ID 54933 ChemIDplus: ID 003303319 ChemSpider: ID 69263 EPA DSSTox: ID DTXSID00186696 EROP-Moscow: ID E06688 FeptideDB: ID 3182; 8326 FooDB: ID FDB111960 HMDB: ID HMDB0028933 J-GLOBAL: ID 200907023863170060 KEGG: ID C11332 KNApSAcK: ID C00038887 MeSH: term L-leucyl-L-leucine MetaCyc: Compound L-leucyl-L-leucine Nikkaji: ID J80.685D PlantPepDB: ID PPepDB_3428 PubChem: CID 76807 SAPdb: ID 1636; 1637 SATPdb: ID satpdb13702 SureChEMBL: ID SCHEMBL235250 ZINC: ID ZINC01532219 |