BIOPEP-UWM: Report

ID 3198
Name Antiviral peptide
sequence
GICACRRRFCPNSERFSGYCRVNGARYVRCCSRR
Function:
Anitiviral activity against Haemophilus influenzae
 
Number of residues
34
Activity code
avi
Activity :
antiviral
Chemical mass 4003.6299 Monoisotopic mass 4000.8705
EC50 :
0.00 µM


Bibliographic data:
Authors
Selsted M. E., Brown D. M., DeLange R. J., Harwig S. S., Lehrer R. I.
Title
Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. J. Biol. Chem., 260, 4579-4584, 1985
Year Source
1985 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(NC(=O)CNC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CS)NC(=O)[C@]([H])(Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CS)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CS)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(CS)NC(=O)[C@@]([H])(NC(=O)CN)[C@@H](C)CC)C(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C163H265N63O44S6/c1-9-80(6)123(223-117(234)66-164)152(267)221-108(72-271)144(259)197-82(8)125(240)217-109(73-272)145(260)204-91(32-18-52-187-157(171)172)129(244)200-90(31-17-51-186-156(169)170)128(243)201-93(34-20-54-189-159(175)176)132(247)210-101(61-84-28-14-11-15-29-84)139(254)222-113(77-276)153(268)226-59-25-39-114(226)149(264)212-104(65-116(166)233)140(255)215-106(70-228)143(258)206-97(48-49-120(237)238)135(250)202-94(35-21-55-190-160(177)178)133(248)209-100(60-83-26-12-10-13-27-83)138(253)214-105(69-227)127(242)195-68-119(236)198-99(62-85-40-44-87(230)45-41-85)137(252)219-110(74-273)146(261)205-96(37-23-57-192-162(181)182)136(251)224-122(79(4)5)151(266)213-103(64-115(165)232)126(241)194-67-118(235)196-81(7)124(239)199-89(30-16-50-185-155(167)168)131(246)211-102(63-86-42-46-88(231)47-43-86)141(256)225-121(78(2)3)150(265)207-95(36-22-56-191-161(179)180)134(249)218-112(76-275)148(263)220-111(75-274)147(262)216-107(71-229)142(257)203-92(33-19-53-188-158(173)174)130(245)208-98(154(269)270)38-24-58-193-163(183)184/h10-15,26-29,40-47,78-82,89-114,121-123,227-231,271-276H,9,16-25,30-39,48-77,164H2,1-8H3,(H2,165,232)(H2,166,233)(H,194,241)(H,195,242)(H,196,235)(H,197,259)(H,198,236)(H,199,239)(H,200,244)(H,201,243)(H,202,250)(H,203,257)(H,204,260)(H,205,261)(H,206,258)(H,207,265)(H,208,245)(H,209,248)(H,210,247)(H,211,246)(H,212,264)(H,213,266)(H,214,253)(H,215,255)(H,216,262)(H,217,240)(H,218,249)(H,219,252)(H,220,263)(H,221,267)(H,222,254)(H,223,234)(H,224,251)(H,225,256)(H,237,238)(H,269,270)(H4,167,168,185)(H4,169,170,186)(H4,171,172,187)(H4,173,174,188)(H4,175,176,189)(H4,177,178,190)(H4,179,180,191)(H4,181,182,192)(H4,183,184,193)/t80-,81-,82-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,121-,122-,123-/m0/s1

InChIKey=WAPXALUOWCTJOV-ZEXSPGRCSA-N


Disulphide bonds: 3-31; 5-20; 10-30 according to the PeptideDB database

Antifungal peptide according to the APD database
Antibacterai peptide according to the APD database; the BIOPEP-UWM database of bioactive peptides (ID 2765)


Database reference:
APD: ID AP00217

BIOPEP-UWM database of bioactive peptides: ID 2765

CAMP: ID CAMPSQ756

EROP-Moscow: ID E00588

PeptideDB: ID PEP03716

SATPdb: ID satpdb15137