BIOPEP-UWM: Report

ID 3213
Name Antithrombotic peptide
sequence
HLGGAKQAGDV

Function:
Inhibitor of platelet aggregation
 
Number of residues
11
Activity code
at
Activity :
antithrombotic
Chemical mass 1052.1390 Monoisotopic mass 1051.5394
EC50 :
0.00 µM



Bibliographic data:
Authors
Cierniewski C. S., Byzova T., Papierak M., Haas T. A., Niewiarowska J., Zhang L., Cieslak M., Plow E. F.
Title
Peptide ligands can bind to distinct sites in integrin alphaIIb-beta3 and elicit different functional responses. J Biol. Chem., 274, 16923-16932, 1999
Year Source
1999 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=C[N]([H])C=N1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)O

InChI=1S/C44H73N15O15/c1-21(2)13-29(58-39(68)26(46)14-25-16-48-20-52-25)40(69)51-17-32(61)49-18-33(62)53-24(6)38(67)56-27(9-7-8-12-45)42(71)57-28(10-11-31(47)60)41(70)54-23(5)37(66)50-19-34(63)55-30(15-35(64)65)43(72)59-36(22(3)4)44(73)74/h16,20-24,26-30,36H,7-15,17-19,45-46H2,1-6H3,(H2,47,60)(H,48,52)(H,49,61)(H,50,66)(H,51,69)(H,53,62)(H,54,70)(H,55,63)(H,56,67)(H,57,71)(H,58,68)(H,59,72)(H,64,65)(H,73,74)/t23-,24-,26-,27-,28-,29-,30-,36-/m0/s1

InChIKey=CVSUOIMABBJXJG-GGBOURJCSA-N



Database reference:
PepBank: Peptide HLGGAKQAGDV