BIOPEP-UWM: Report

ID 3251
Name beta-casomorphin-11 (60-70)
sequence
YPFPGPIPNSL
Function:
Opioid agonist
 
Number of residues
11
Activity code
op1
Activity :
opioid agonist
Chemical mass 1201.3663 Monoisotopic mass 1200.6159
EC50 :
10.00 µM


Bibliographic data:
Authors
Meisel H.
Title
Chemical characterization and opioid activity of an exorphin isolated from in vivo digests of casein. FEBS Lett., 196, 223-227, 1986
Year Source
1986 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C59H84N12O15/c1-5-34(4)49(58(84)71-26-12-18-46(71)53(79)63-39(30-47(61)74)50(76)66-42(32-72)51(77)65-41(59(85)86)27-33(2)3)67-55(81)44-16-9-23-68(44)48(75)31-62-52(78)43-15-10-25-70(43)57(83)40(29-35-13-7-6-8-14-35)64-54(80)45-17-11-24-69(45)56(82)38(60)28-36-19-21-37(73)22-20-36/h6-8,13-14,19-22,33-34,38-46,49,72-73H,5,9-12,15-18,23-32,60H2,1-4H3,(H2,61,74)(H,62,78)(H,63,79)(H,64,80)(H,65,77)(H,66,76)(H,67,81)(H,85,86)/t34-,38-,39-,40-,41-,42-,43-,44-,45-,46-,49-/m0/s1

InChIKey=LGPVSBODEPGJNA-XPPITOOHSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database


Database reference:
ACToR: ID 101554-61-4

AHTPDB: ID 1942

BioPepDB: ID biopep01598; biopep04799

ChemIDplus: ID 101554-61-4

ChemSpider: ID 113464

CTD: ID 101554-61-4

eChemPortal: ID 101554-61-4

EPA DSSTox: ID DTXSID50143996

EROP-Moscow: ID E00610

FeptideDB: ID 3251

MeSH: Term beta-casomorphin 11

PubChem: CID 127934

SATPdb: ID satpdb26795