BIOPEP-UWM: Report

ID 3255
Name beta-lactorphin (102-105) ACE inhibitor
sequence
YLLF
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 554.6760 Monoisotopic mass 554.3094
IC50 :
172.00 µM


Bibliographic data:
Authors
Mullally M. M., Meisel H., FitzGerald R. J.
Title
Synthetic peptides corresponding to alpha-lactalbumin and beta-lactoglobulin sequences with angiotensin-I-converting enzyme inhibitory activity. Biol. Chem. Hoppe-Seyler, 377, 259-261, 1996
Year Source
1996 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(O)=O

InChI=1S/C30H42N4O6/c1-18(2)14-24(32-27(36)23(31)16-21-10-12-22(35)13-11-21)28(37)33-25(15-19(3)4)29(38)34-26(30(39)40)17-20-8-6-5-7-9-20/h5-13,18-19,23-26,35H,14-17,31H2,1-4H3,(H,32,36)(H,33,37)(H,34,38)(H,39,40)/t23-,24-,25-,26-/m0/s1

InChIKey=QKWJBYNAISXCRK-CQJMVLFOSA-N


Opioid agonist according to the BIOPEP-UWM database of bioactive peptides (ID 3256); the MBPDB database
Osteoanabolic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10409)


Database reference:
AHTPDB: ID 1212, 1317, 1941, 4129, 4265, 4879, 5306, 6199, 6337

BioPepDB: ID biopep01583; biopep04754

BIOPEP-UWM database of bioactive peptides: ID 3256; 10409

ChemSpider: ID 57558124

DFBP: ID DFBPACEI0019; DFBPACEI1748; DFBPMUFU0010

EPA DSSTox: DTXSID30649522

EROP-Moscow: ID E07063

FeptideDB: ID 3255; 3256

J-GLOBAL: ID 200907009482834067

MBPDB: Peptide YLLF

Nikkaji: ID J1.559.021A

PepBank: Peptide YLLF

PubChem: CID 25261293

SATPdb: ID satpdb21332