BIOPEP-UWM: Report

ID 3341
Name ACE inhibitor
sequence
FQP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 390.4325 Monoisotopic mass 390.1897
EC50 :
0.00 µM



Bibliographic data:
Authors
Yokoyama K., Chiba H., and Yoshikawa M.
Title
Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotech. Biochem., 56, 1541-1545, 1992
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C19H26N4O5/c20-13(11-12-5-2-1-3-6-12)17(25)22-14(8-9-16(21)24)18(26)23-10-4-7-15(23)19(27)28/h1-3,5-6,13-15H,4,7-11,20H2,(H2,21,24)(H,22,25)(H,27,28)/t13-,14-,15-/m0/s1

InChIKey=IDUCUXTUHHIQIP-KKUMJFAQSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-00.

Peptide found also in amaranth protein hydrolysate.

Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111



Database reference: