BIOPEP-UWM: Report

ID 3343
Name ACE inhibitor
sequence
ALPHA
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 507.5817 Monoisotopic mass 507.2797
EC50 :
10.00 µM


Bibliographic data:
Authors
Yokoyama K., Chiba H., Yoshikawa M.
Title
Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotech. Biochem., 56, 1541-1545, 1992
Year Source
1992 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)N1[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C)Cc2[nH]cnc2)CCC1)CC(C)C)C

InChI=1S/C23H37N7O6/c1-12(2)8-17(29-19(31)13(3)24)22(34)30-7-5-6-18(30)21(33)28-16(9-15-10-25-11-26-15)20(32)27-14(4)23(35)36/h10-14,16-18H,5-9,24H2,1-4H3,(H,25,26)(H,27,32)(H,28,33)(H,29,31)(H,35,36)/t13-,14-,16-,17-,18-/m0/s1

InChIKey: NIBZGHPXKYHPHI-IAVJCBSLSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 1067, 5309, 5310, 5659, 5672, 6340

BRENDA: Ligand Ala-Leu-Pro-His-Ala

EROP-Moscow: ID E01435

PepBank: Peptide ALPHA

SATPdb: ID satpdb20821

UNPD: ID UNPD186799