BIOPEP-UWM: Report

ID 3348
Name ACE inhibitor
sequence
IWHHT
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 692.7635 Monoisotopic mass 692.3385
IC50 :
5.80 µM


Bibliographic data:
Authors
Yokoyama K., Chiba H., and Yoshikawa M., 1992
Title
Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotech. Biochem., 56, 1541-1545
Year Source
1992 Journal


Additional information:

BIOPEP database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)[C@H](O)C)Cc1[nH]cnc1)Cc1[nH]cnc1)Cc1c[nH]c2c1cccc2)[C@H](CC)C

InChI=1S/C33H44N10O7/c1-4-17(2)27(34)32(48)42-24(9-19-12-37-23-8-6-5-7-22(19)23)29(45)40-25(10-20-13-35-15-38-20)30(46)41-26(11-21-14-36-16-39-21)31(47)43-28(18(3)44)33(49)50/h5-8,12-18,24-28,37,44H,4,9-11,34H2,1-3H3,(H,35,38)(H,36,39)(H,40,45)(H,41,46)(H,42,48)(H,43,47)(H,49,50)/t17-,18+,24-,25-,26-,27-,28-/m0/s1

InChIKey: OLSRROIYCKGQLR-DIRMYTRESA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001


Database reference:
AHTPDB: ID 1066; 2140; 2344; 4223; 5007; 5323; 5658; 6345

ChemSpider: ID 8007210

EROP-Moscow: ID E01433

PepBank: Peptide IWHHT

PubChem: ID 9831478

SATPdb: satpdb22414