BIOPEP-UWM: Report
| ID | 3349 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 356.4591 | Monoisotopic mass | 356.2416 | |
| EC50 : | 6.90 µM |
|||
| Bibliographic data: | |
| Authors | |
| Yokoyama K., Chiba H., and Yoshikawa M., 1992 | |
| Title | |
| Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito. Biosci. Biotech. Biochem., 56, 1541-1545 | |
| Year | Source |
| 1992 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(CCCCN)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C17H32N4O4/c1-3-11(2)14(19)15(22)20-12(7-4-5-9-18)16(23)21-10-6-8-13(21)17(24)25/h11-14H,3-10,18-19H2,1-2H3,(H,20,22)(H,24,25)/t11-,12-,13-,14-/m0/s1 InChIKey=GLYJPWIRLBAIJH-XUXIUFHCSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 IC50(EC50) of the peptide ranges from 2.5 to 7. Loponen J., 2004, Angiotensin converting enzyme inhibitory peptides in Finnish cereals: a database survey. Agric. Food Sci., 13, 39-45 Jimsheena V. K., Gowda L. R., 2010, Arachin derived peptides as selective angiotensin I-converting enzyme (ACE) inhibitors: structure-activity relationship. Peptides, 31, 1165-1176 |
| Database reference: |