BIOPEP-UWM: Report
ID | 3373 |
Name | ACE inhibitor from beta-CN |
sequence |
Function: | |||
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
Number of residues | 3 |
Activity code | ah |
Activity : | ACE inhibitor |
|||
Chemical mass | 399.4442 | Monoisotopic mass | 399.2224 | |
IC50 : | 401.00 µM |
Bibliographic data: | |
Authors | |
Meisel H. | |
Title | |
Casokinins as bioactive peptides in the primary strucure of casein. In: Food proteins, structure and functionality. ed. Schwenke K. D., Mothes R., VCh, Weinheim - New York - Basel - Cambridge - Tokyo, pp 67-75, 1993 | |
Year | Source |
1993 | book |
Additional information: |
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](CCCNC(N)=N)(NC(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@]1([H])CCCN1)C(O)=O InChI=1S/C16H29N7O5/c17-12(24)6-5-10(22-13(25)9-3-1-7-20-9)14(26)23-11(15(27)28)4-2-8-21-16(18)19/h9-11,20H,1-8H2,(H2,17,24)(H,22,25)(H,23,26)(H,27,28)(H4,18,19,21)/t9-,10-,11-/m0/s1 InChIKey=LSIWVWRUTKPXDS-DCAQKATOSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
Database reference: |
AHTPDB: ID 1178, 3386, 4010, 4103, 5617, 5856, 6358, EROP-Moscow: ID E09261 FeptideDB: ID 3373 PubChem: CID 145457442 SATPdb: ID satpdb28276 |