BIOPEP-UWM: Report
| ID | 3373 |
| Name | ACE inhibitor from beta-CN |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 399.4442 | Monoisotopic mass | 399.2224 | |
| IC50 : | 401.00 µM |
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| Bibliographic data: | |
| Authors | |
| Meisel H. | |
| Title | |
| Casokinins as bioactive peptides in the primary strucure of casein. In: Food proteins, structure and functionality. ed. Schwenke K. D., Mothes R., VCh, Weinheim - New York - Basel - Cambridge - Tokyo, pp 67-75, 1993 | |
| Year | Source |
| 1993 | book |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](CCCNC(N)=N)(NC(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@]1([H])CCCN1)C(O)=O InChI=1S/C16H29N7O5/c17-12(24)6-5-10(22-13(25)9-3-1-7-20-9)14(26)23-11(15(27)28)4-2-8-21-16(18)19/h9-11,20H,1-8H2,(H2,17,24)(H,22,25)(H,23,26)(H,27,28)(H4,18,19,21)/t9-,10-,11-/m0/s1 InChIKey=LSIWVWRUTKPXDS-DCAQKATOSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
| Database reference: |
| AHTPDB: ID 1178, 3386, 4010, 4103, 5617, 5856, 6358, EROP-Moscow: ID E09261 FeptideDB: ID 3373 PubChem: CID 145457442 SATPdb: ID satpdb28276 |