BIOPEP-UWM: Report

ID 3377
Name ACE inhibitor (from bovine alphas1-CN)
sequence
FGK

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 350.4117 Monoisotopic mass 350.1948
IC50 :
160.00 µM



Bibliographic data:
Authors
Maruyama S., Mitachi H., Tanaka H., Tomizuka N., Suzuki H.
Title
Studies on the active site and antihypertensive activity of angiotensin I-converting enzyme inhibitors derived from casein. Agric. Biol. Chem., 51, 1581-1586, 1987
Year Source
1987 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(Cc1ccccc1)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(O)=O

InChI=1S/C17H26N4O4/c18-9-5-4-8-14(17(24)25)21-15(22)11-20-16(23)13(19)10-12-6-2-1-3-7-12/h1-3,6-7,13-14H,4-5,8-11,18-19H2,(H,20,23)(H,21,22)(H,24,25)/t13-,14-/m0/s1

InChIKey=HBGFEEQFVBWYJQ-KBPBESRZSA-N



Database reference:
AHTPDB: ID 1134, 1604, 2246, 3480, 4384, 4779, 5201, 5852, 6361

BindingDB: ID 50348851

BioPepDB: ID biopep00241

BRENDA: Ligand Phe-Gly-Lys

ChEBI: ID 161534

ChEMBL: ID CHEMBL1807685

ChemSpider: ID 26617383

EROP-Moscow: ID E14540

FeptideDB: ID 3377

PubChem: CID 15458467

SATPdb: ID satpdb17099