BIOPEP-UWM: Report
| ID | 3378 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 328.3665 | Monoisotopic mass | 328.1854 | |
| EC50 : | 19.90 µM |
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| Bibliographic data: | |
| Authors | |
| Matsufuji H., Matsui T., Seki E., Osajima K., Nakashima M., Osajima Y. | |
| Title | |
| Angiotensin I-converting enzyme inhibitory peptides in an alkaline proteinase hydrolysate derived from sardine muscle. Biosci. Biotech. Biochem., 58, 2244-2245, 1994 | |
| Year | Source |
| 1994 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](CCCNC(N)=N)(NC(=O)CN)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C13H24N6O4/c14-7-10(20)18-8(3-1-5-17-13(15)16)11(21)19-6-2-4-9(19)12(22)23/h8-9H,1-7,14H2,(H,18,20)(H,22,23)(H4,15,16,17)/t8-,9-/m0/s1 InChIKey=VXKCPBPQEKKERH-IUCAKERBSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 Bitter peptide according to BIOPEP database of sensory peptides and amino acids |
| Database reference: |
| AHTPDB: ID 1100; 1139; 1529; 3082; 3492; 4074; 4545; 4630; 4826; 5081; 5211; 5590; 6179; 6362 BIOPEP database of sensory peptides and amino acids: ID 29 EROP-Moscow: ID E01338 |