BIOPEP-UWM: Report
ID | 3385 |
Name | ACE inhibitor |
sequence |
Function: | |||
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
Number of residues | 2 |
Activity code | ah |
Activity : | ACE inhibitor |
|||
Chemical mass | 296.3855 | Monoisotopic mass | 296.1190 | |
EC50 : | 45.00 µM |
Bibliographic data: | |
Authors | |
Matsufuji H., Matsui T., Seki E., Osajima K., Nakashima M., Osajima Y. | |
Title | |
Angiotensin I-converting enzyme inhibitory peptides in an alkaline proteinase hydrolysate derived from sardine muscle. Biosci. Biotech. Biochem., 58, 2244-2245, 1994 | |
Year | Source |
1994 | Journal |
Additional information: |
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCSC)C(=O)N[C@@]([H])(Cc1ccccc1)C(O)=O InChI=1S/C14H20N2O3S/c1-20-8-7-11(15)13(17)16-12(14(18)19)9-10-5-3-2-4-6-10/h2-6,11-12H,7-9,15H2,1H3,(H,16,17)(H,18,19)/t11-,12-/m0/s1 InChIKey=HGCNKOLVKRAVHD-RYUDHWBXSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Another value of peptide IC50(EC50) = 1,45 uM. Wu H., He H.-L., Chen X.-L., Sun C.-Y., Zhang Y.-Z., Zhou B.-C., 2008, Purification and identification of novel angiotensin-I-converting enzyme inhibitory peptides from shark meat hydrolysate. Process Biochem., 43, 457-461 Isolated from shark meat Wu H., He H.-L., Chen X.-L., Sun C.-Y., Zhang Y.-Z., Zhou B.-C., 2008, Purification and identification of novel angiotensin-I-converting enzyme inhibitory peptides from shark meat hydrolysate. Process Biochem., 43, 457-461 Found in amaranth protein hydrolysates Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
Database reference: |