BIOPEP-UWM: Report
| ID | 3406 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
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| Chemical mass | 287.3114 | Monoisotopic mass | 287.1476 | |
| EC50 : | 3.50 µM |
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| Bibliographic data: | |
| Authors | |
| Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y. | |
| Title | |
| Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53, 2107-2114, 1989 | |
| Year | Source |
| 1989 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C)(O)[C@]([H])(N)C(=O)N[C@@]([H])(C)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C12H21N3O5/c1-6(14-10(17)9(13)7(2)16)11(18)15-5-3-4-8(15)12(19)20/h6-9,16H,3-5,13H2,1-2H3,(H,14,17)(H,19,20)/t6-,7+,8-,9-/m0/s1 InChIKey=LVHHEVGYAZGXDE-KZVJFYERSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
| Database reference: |