BIOPEP-UWM: Report
ID | 3410 |
Name | ACE inhibitor |
sequence |
Function: | |||
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
Number of residues | 4 |
Activity code | ah |
Activity : | ACE inhibitor |
|||
Chemical mass | 396.4799 | Monoisotopic mass | 396.2365 | |
EC50 : | 0.00 µM |
Bibliographic data: | |
Authors | |
Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y. | |
Title | |
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53, 2107-2114, 1989 | |
Year | Source |
1989 | Journal |
Additional information: |
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](C)(N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C19H32N4O5/c1-11(2)10-13(21-16(24)12(3)20)17(25)22-8-4-6-14(22)18(26)23-9-5-7-15(23)19(27)28/h11-15H,4-10,20H2,1-3H3,(H,21,24)(H,27,28)/t12-,13-,14-,15-/m0/s1 InChIKey=VLTMSZWGNUQYNC-AJNGGQMLSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
Database reference: |