BIOPEP-UWM: Report

ID 3458
Name Prolyl endopeptidase inhibitor
sequence
GPGG

Function:
Inhibitor of Prolyl Endopeptidase (PEP) (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
4
Activity code
am
Activity :
antiamnestic
Chemical mass 286.2837 Monoisotopic mass 286.1273
EC50 :
0.00 µM



Bibliographic data:
Authors
Ashmarin I. P., Karazeeva E. P., Lyapina L. A., Samonina G. E.
Title
The simplest proline-containing peptides PG, GP, PGP and GPGG: regulatory activity and possible source of biosynthesis. Biochemistry-Moscow, 63, 119-124
Year Source
1998 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@]1(CCCN1C(=O)CN)C(=O)NCC(=O)NCC(O)=O

InChI=1S/C11H18N4O5/c12-4-9(17)15-3-1-2-7(15)11(20)14-5-8(16)13-6-10(18)19/h7H,1-6,12H2,(H,13,16)(H,14,20)(H,18,19)/t7-/m0/s1

InChIKey=PEZMQPADLFXCJJ-ZETCQYMHSA-N


Information concerning Prolyl Endopeptidase (synonym: Proline-Specific Endopeptidase (abbrev. PEP) (EC 3.4.21.26) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: S09.001


Peptide regulating the stomach mucosal membrane activity according to the BIOPEP-UWM database of bioactive peptides ( ID 2755);
Antithrombotic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3462)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 2755; 3462

ChemIDplus: ID 013054030

ChemSpider: ID 87411

PubChem: CID 96811

ZINC: ID ZINC04545910