BIOPEP-UWM: Report

ID 3460
Name Prolyl endopeptidase inhibitor
sequence
PG

Function:
Inhibitor of Prolyl Endopeptidase (PEP) (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
2
Activity code
am
Activity :
antiamnestic
Chemical mass 172.1813 Monoisotopic mass 172.0845
EC50 :
0.00 µM



Bibliographic data:
Authors
Ashmarin I. P., Karazeeva E. P., Lyapina L. A., Samonina G. E.
Title
The simplest proline-containing peptides PG, GP, PGP and GPGG: regulatory activity and possible source of biosynthesis. Biochemistry-Moscow, 63, 119-124, 1998
Year Source
1998 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)NCC(=O)O

InChI=1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1

InChIKey: RNKSNIBMTUYWSH-YFKPBYRVSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 7625); the ChEMBL database; the EROP-Moscow database (ID E09277)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8855); the BRENDA database
Antithrombotic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3285)
Peptide regulating the stomach mucosal membrane activity according to the BIOPEP-UWM database of bioactive peptides (ID 2754)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 481), the ChEMBL database; the EROP-Moscow database (ID E03694)



Database reference:
ACToR: ID 2578-57-6

AHTPDB: ID 1493, 3060, 3143, 3151, 3257, 3428, 3524, 3613, 3827, 4001, 4395, 4533, 4669, 6612

BindingDB: ID 50188480

BioPepDB: ID biopep01043

BIOPEP-UWM database of bioactive peptides: ID 3285; 3285; 7625, 8855

BIOPEP-UWM database of sensory peptides and amino acids: ID 481

BRENDA: Ligand Pro-Gly

ChEBI: ID 61695

ChEMBL: ID CHEMBL59426

ChemSpider: ID 4932143

EROP-Moscow: ID E03694; E02533; E09277

FDA SRS: ID 42521I3FYC

Golm: ID 654E0B74-C991-4228-B739-3A3AB574E291

J-GLOBAL: ID 200907040238523577

Nikkaji: ID J149.651D

PubChem: CID 6426709

Rhea: ID 61696

SATPdb: ID satpdb10032

SureChEMBL: ID SCHEMBL620067

ZINC: ID ZINC000004899418