BIOPEP-UWM: Report

ID 3483
Name ACE inhibitors derived from yeast GADPH
sequence
GKKIATYQER

Function:
 
Number of residues
10
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1193.3492 Monoisotopic mass 1192.6544
EC50 :
2.00 µM



Bibliographic data:
Authors
Kohama Y., Nagase Y., Oka H., Nakagawa T., Teramoto T., Murayama N., Tsujibo H.,
Title
Production of angiotensin-converting enzyme inhibitors from baker's yeasts Glyceraldehyde-3-phosphate Dehydrogenase. J. Pharmacobio-Dyn. 13, 766-771
Year Source
1990 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)[C@]([H])(C)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCCN)NC(=O)CN)[C@@]([H])(C)CC)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O

InChI=1S/C52H88N16O16/c1-5-27(2)41(67-47(79)33(12-7-9-23-54)62-44(76)32(11-6-8-22-53)61-39(72)26-55)49(81)60-28(3)43(75)68-42(29(4)69)50(82)66-37(25-30-14-16-31(70)17-15-30)48(80)64-34(18-20-38(56)71)45(77)63-35(19-21-40(73)74)46(78)65-36(51(83)84)13-10-24-59-52(57)58/h14-17,27-29,32-37,41-42,69-70H,5-13,18-26,53-55H2,1-4H3,(H2,56,71)(H,60,81)(H,61,72)(H,62,76)(H,63,77)(H,64,80)(H,65,78)(H,66,82)(H,67,79)(H,68,75)(H,73,74)(H,83,84)(H4,57,58,59)/t27-,28-,29+,32-,33-,34-,35-,36-,37-,41-,42-/m0/s1

InChIKey=OSXRNCSRDFEOTA-PBEFRTBXSA-N



Database reference: