BIOPEP-UWM: Report

ID 3485
Name ACE inhibitors derived from yeast GADPH
sequence
PANLPWGSSNV
Function:
 
Number of residues
11
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1141.2303 Monoisotopic mass 1140.5546
EC50 :
18.00 µM


Bibliographic data:
Authors
Kohama Y., Nagase Y., Oka H., Nakagawa T., Teramoto T., Murayama N., Tsujibo H.,
Title
Production of angiotensin-converting enzyme inhibitors from baker's yeasts Glyceraldehyde-3-phosphate Dehydrogenase. J. Pharmacobio-Dyn. 13, 766-771
Year Source
1990 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(NC(=O)[C@]1([H])CCCN1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(O)=O

InChI=1S/C51H76N14O16/c1-24(2)16-34(62-45(74)32(18-38(52)68)59-42(71)26(5)57-44(73)30-12-8-14-54-30)50(79)65-15-9-13-37(65)49(78)61-31(17-27-20-55-29-11-7-6-10-28(27)29)43(72)56-21-40(70)58-35(22-66)47(76)63-36(23-67)48(77)60-33(19-39(53)69)46(75)64-41(25(3)4)51(80)81/h6-7,10-11,20,24-26,30-37,41,54-55,66-67H,8-9,12-19,21-23H2,1-5H3,(H2,52,68)(H2,53,69)(H,56,72)(H,57,73)(H,58,70)(H,59,71)(H,60,77)(H,61,78)(H,62,74)(H,63,76)(H,64,75)(H,80,81)/t26-,30-,31-,32-,33-,34-,35-,36-,37-,41-/m0/s1

InChIKey=KGDYXGWOWUNPTR-LUTHQIGCSA-N


Database reference: