BIOPEP-UWM: Report

ID 3501
Name ACE inhibitor from alphas1-casein
sequence
AYFYPE
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 788.8408 Monoisotopic mass 788.3369
IC50 :
106.00 µM


Bibliographic data:
Authors
Yamamoto N., Akino A., Takano T.
Title
Antihypertensive effects of peptides derived from casein by an extracellular proteinase from Lactobacillus helveticus CP790. J. Dairy Sci., 77, 917-922, 1994
Year Source
1994 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(N)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(O)=O)C(O)=O

InChI=1S/C40H48N6O11/c1-23(41)35(51)43-30(21-25-9-13-27(47)14-10-25)36(52)44-31(20-24-6-3-2-4-7-24)37(53)45-32(22-26-11-15-28(48)16-12-26)39(55)46-19-5-8-33(46)38(54)42-29(40(56)57)17-18-34(49)50/h2-4,6-7,9-16,23,29-33,47-48H,5,8,17-22,41H2,1H3,(H,42,54)(H,43,51)(H,44,52)(H,45,53)(H,49,50)(H,56,57)/t23-,29-,30-,31-,32-,33-/m0/s1

InChIKey=MJSMBGMARRSHGO-XDGMXVDYSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10061); the MBPDB database


Database reference:
AHTPDB: ID 1129, 2451, 6420

BioPepDB: ID biopep00103

BIOPEP-UWM database of bioactive peptides: ID 10061

ChemSpider: ID 8345049

EROP-Moscow: ID E07442

FeptideDB: ID 3501

J-GLOBAL: ID 200907066078620499

MBPDB: Peptide AYFYPE

Nikkaji: J1.716.449J

PubChem: CID 10169544