BIOPEP-UWM: Report
| ID | 3506 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
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| Chemical mass | 300.3531 | Monoisotopic mass | 300.1792 | |
| EC50 : | 352.00 µM |
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| Bibliographic data: | |
| Authors | |
| Abubakar A., Saito T., Kitazawa H., Kawai Y., Itoh T. | |
| Title | |
| Structural analysis of new antihypertensive peptides derived from cheese whey protein by proteinase K digestion. J. Dairy Sci., 81(12), 3131-3138 (1998) | |
| Year | Source |
| 1998 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](CCCCN)(NC(=O)CN)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C13H24N4O4/c14-6-2-1-4-9(16-11(18)8-15)12(19)17-7-3-5-10(17)13(20)21/h9-10H,1-8,14-15H2,(H,16,18)(H,20,21)/t9-,10-/m0/s1 InChIKey=WDEHMRNSGHVNOH-UWVGGRQHSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Peptide is a fragment 18-20 of bovine beta-casein. Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 Predicted as bitterness suppressing peptide according to the BIOPEP-UWM Virtual database (ID 137) |
| Database reference: |
| AHTPDB: ID 1587, 1663, 2252, 2578, 2852, 3924, 4073, 4797, 5207, 5564, 5589, 5946, 6425, 6863 BindingDB: ID 50049795 BIOPEP-UWM Virtual database: ID 137 ChEMBL: ID CHEMBL3322008 ChemSpider: ID 58113011 EROP-Moscow: ID E09244 FeptideDB: ID 3506 PlantPepDB: ID PPepDB_2909 PubChem: CID 53308269 SATPdb: ID satpdb15034 ZINC: ID ZINC000039817963 |