BIOPEP-UWM: Report
| ID | 3515 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 295.2905 | Monoisotopic mass | 295.1164 | |
| EC50 : | 1.30 µM |
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| Bibliographic data: | |
| Authors | |
| Saito Y., Wanezaki K., Kawato A., Imayasu S. | |
| Title | |
| Structure and activity of angiotensin I converting enzyme inhibitory peptides from sake and sake lees. Biosci. Biotech. Biochem., 58(10), 1767-1771(1994) | |
| Year | Source |
| 1994 | Journal |
| Additional information: |
| BIOPEP database of bioactive peptides SMILES: NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O InChI=1S/C13H17N3O5/c14-6-11(18)15-7-12(19)16-10(13(20)21)5-8-1-3-9(17)4-2-8/h1-4,10,17H,5-7,14H2,(H,15,18)(H,16,19)(H,20,21)/t10-/m0/s1 InChIKey: INLIXXRWNUKVCF-JTQLQIEISA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Inhibitor of citruline uptake in yeasts according to ChEMBL database Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
| Database reference: |
| AHTPDB: ID 1137; 1593; 3484; 3920; 4562; 4862; 5476; 5588; 6434 BIOPEP database of sensory peptides and amino acids: ID 36 BRENDA: Ligand Gly-Gly-L-Tyr ChEMBL: ID CHEMBL1221778 ChemSpider: ID 5360628 EROP-Moscow: ID E09243 PubChem: ID 6992498 ZINC: ID ZINC01576190 |