BIOPEP-UWM: Report

ID 3530
Name ACE inhibitor (fr. of alpha s1-casein, 194-199)
sequence
TTMPLW
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 747.9008 Monoisotopic mass 747.3613
IC50 :
16.00 µM


Bibliographic data:
Authors
Maruyama S., Mitachi H., Awaya J., Kurono M., Tomizuka N., Suzuki H.
Title
Angiotensin I-converting enzyme inhibitory activity of the C-terminal hexapeptide of αs1-casein. Agric. Biol. Chem., 51, 2557-2561, 1987
Year Source
1987 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](CC1=CNC2=C1C=CC=C2)(NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CCSC)NC(=O)[C@@]([H])(NC(=O)[C@@]([H])(N)[C@@H](C)O)[C@@H](C)O)C(O)=O

InChI=1S/C35H53N7O9S/c1-18(2)15-25(30(45)40-26(35(50)51)16-21-17-37-23-10-7-6-9-22(21)23)39-31(46)27-11-8-13-42(27)34(49)24(12-14-52-5)38-33(48)29(20(4)44)41-32(47)28(36)19(3)43/h6-7,9-10,17-20,24-29,37,43-44H,8,11-16,36H2,1-5H3,(H,38,48)(H,39,46)(H,40,45)(H,41,47)(H,50,51)/t19-,20-,24+,25+,26+,27+,28+,29+/m1/s1

InChIKey=QGGBSIAUWWUJLC-QAPARMCSSA-N


Immunomodulating peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8172); the EROP-Moscow database
Antibacterial peptide according to the BIOPEP-UWM database of bioactive peptides (ID 3127); the MBPDB database
Antifungal peptide according to the BIOPEP-UWM database of bioactive peptides (ID 9619); the mBPDB database


Database reference:
AHTPDB: ID 1191, 1658, 1721, 2387, 3611, 4143, 4275, 4387, 5015, 5388, 5389, 5559, 5835, 5906, 6448, 6857

BioPepDB: ID biopep01313; biopep04796

BIOPEP-UWM database of bioactive peptides: ID 3127; 8172; 9619

ChemSpider: ID 8344821

EROP-Moscow: ID E07427

J-GLOBAL: ID 200907072296022943

MBPDB: Peptide TTMPLW

Nikkaji: ID J1.415.010B

PubChem: CID 10169316

SATPdb: ID satpdb11396