BIOPEP-UWM: Report
| ID | 3531 |
| Name | ACE inhibitor from alphas1-CN |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 414.4968 | Monoisotopic mass | 414.2260 | |
| EC50 : | 36.00 µM |
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| Bibliographic data: | |
| Authors | |
| Maruyama S., Mitachi H., Tanaka H., Tomizuka N., Suzuki H. | |
| Title | |
| Angiotensin-I converting enzyme inhibitory activity of the C-terminal hexapeptide of a-casein. Agric.Biol.Chem., 51, 2557-2561(1987) | |
| Year | Source |
| 1987 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O InChI=1S/C22H30N4O4/c1-13(2)10-18(25-20(27)17-8-5-9-23-17)21(28)26-19(22(29)30)11-14-12-24-16-7-4-3-6-15(14)16/h3-4,6-7,12-13,17-19,23-24H,5,8-11H2,1-2H3,(H,25,27)(H,26,28)(H,29,30)/t17-,18-,19-/m0/s1 InChIKey=SRBFGSGDNNQABI-FHWLQOOXSA-N IC50(EC50)=22 from: Meisel H., Walsh D. J., Murray B., FitzGerald R. J.(2006). ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315. Predicted ligand of SARS-CoV-2 parent protease (EC 3.4.22.69) (MEROPS ID: C30.007) (PDB ID: 6LU7) according to the BIOPEP-UWM Virtual database (ID 56) |
| Database reference: |
| AHTPDB: ID 1177, 1603, 2245, 4388, 5102, 6449 BindingDB: ID BDBM50348864 BioPepDB: ID biopep01069 BIOPEP-UWM Virtual database: ID 56 ChEBI: ID 162451 ChEMBL: ID CHEMBL1807681 ChemSpider: ID 26618431 EROP-Moscow: ID E14733 FeptideDB: ID 3531 J-GLOBAL: ID 200907069117859932 MetaNetX: compound Pro-Leu-Trp; ID MNXM1125041 Nikkaji: ID J2.244.245G PubChem: CID 4320140 SATPdb: ID satpdb17916 SureChEMBL: ID SCHEMBL9653545 ZINC: ID ZINC000039812739 |