BIOPEP-UWM: Report
| ID | 3538 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 301.3379 | Monoisotopic mass | 301.1632 | |
| EC50 : | 10.00 µM |
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| Bibliographic data: | |
| Authors | |
| Miyoshi S., Ishikawa H., Kaneko T., Fukui F., Tanaka H. | |
| Title | |
| Structure and activity of angiotensin-converting enzyme inhibitors in alpha-zein hydrolysate. Agric. Biol. Chem., 55(5), 1313-1318 (1991) | |
| Year | Source |
| 1991 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C13H23N3O5/c1-7(2)10(14)11(18)15-8(6-17)12(19)16-5-3-4-9(16)13(20)21/h7-10,17H,3-6,14H2,1-2H3,(H,15,18)(H,20,21)/t8-,9-,10-/m0/s1 InChIKey=GBIUHAYJGWVNLN-GUBZILKMSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 Predicted ligand of Lipoxin A4 receptor (PDB ID: 6LW5) according to the BIOPEP-UWM Virtual Database |
| Database reference: |
| AHTPDB: ID 1638, 2237, 3153, 4047, 4808, 5265, 5631, 5802, 5872, 6455 BindingDB: ID BDBM50049723 BIOPEP-UWM Virtual database ChEMBL: ID CHEMBL3322003 DFBP: ID DFBPACEI0582; DFBPACEI1935 EROP-Moscow: ID E14714 PubChem: CID 118709853 SATPdb: ID satpdb27914 ZINC: ID ZINC000238763778 |