BIOPEP-UWM: Report
| ID | 3542 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
|||
| Chemical mass | 356.4162 | Monoisotopic mass | 356.2053 | |
| EC50 : | 1.90 µM |
|||
| Bibliographic data: | |
| Authors | |
| Miyoshi S., Ishikawa H., Kaneko T., Fukui F., Tanaka H., Maruyama S. | |
| Title | |
| Structures and activity of angiotensin-converting enzyme inhibitors in an alpha-zein hydrolysate. Agric. Biol. Chem., 55, 1313-1318, 1991 | |
| Year | Source |
| 1991 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C16H28N4O5/c1-9(2)8-10(17)14(22)19-11(5-6-13(18)21)15(23)20-7-3-4-12(20)16(24)25/h9-12H,3-8,17H2,1-2H3,(H2,18,21)(H,19,22)(H,24,25)/t10-,11-,12-/m0/s1 InChIKey=CQGSYZCULZMEDE-SRVKXCTJSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Peptide found in cheese: Tonouchi H., Suzuki M., Uchida M., Oda M., 2008, Antihypertensive effect of an angiotensin converting enzyme inhibitory peptide from enzyme modified cheese. J. Dairy Res., 75, 284-290 found in wheat milling by-products: Nogata Y., Nagamine T., Yanaka M., Ohta H., 2009, Angiotensin I converting enzyme inhibitory peptides produced by autolysis reactions from wheat bran. J. Agric. Food Chem., 57, 6618-6622 found in amaranth protein hydrolysate: Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
| Database reference: |