BIOPEP-UWM: Report
ID | 3546 |
Name | ACE inhibitor |
sequence |
Function: | |||
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
Number of residues | 3 |
Activity code | ah |
Activity : | ACE inhibitor |
|||
Chemical mass | 351.3965 | Monoisotopic mass | 351.1788 | |
EC50 : | 16.00 µM |
Bibliographic data: | |
Authors | |
Miyoshi S., Ishikawa H., Kaneko T., Fukui F., Tanaka H. | |
Title | |
Structure and activity of angiotensin-converting enzyme inhibitors in alpha-zein hydrolysate. Agric. Biol. Chem., 55(5), 1313-1318 (1991) | |
Year | Source |
1991 | Journal |
Additional information: |
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@@](C)(NC(=O)[C@@]([H])(N)C(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(O)=O InChI=1S/C17H25N3O5/c1-9(2)14(18)16(23)19-10(3)15(22)20-13(17(24)25)8-11-4-6-12(21)7-5-11/h4-7,9-10,13-14,21H,8,18H2,1-3H3,(H,19,23)(H,20,22)(H,24,25)/t10-,13-,14-/m0/s1 InChIKey=LABUITCFCAABSV-BPNCWPANSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
Database reference: |