BIOPEP-UWM: Report

ID 3554
Name alpha-lactorphin - ACE inhibitor
sequence
YGLF
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 498.5700 Monoisotopic mass 498.2470
IC50 :
733.30 µM


Bibliographic data:
Authors
Mullally M. M., Meisel H., FitzGerald R. J.
Title
Synthetic peptides corresponding to alpha-lactalbumin and beta-lactoglobulin sequences with angiotensin-I-converting enzyme inhibitory activity. Biol. Chem. Hoppe-Seyler, 377, 259-260, 1996
Year Source
1996 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [C@H](N)(CC1=CC=C(C=C1)O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(O)=O

InChI=1S/C26H34N4O6/c1-16(2)12-21(25(34)30-22(26(35)36)14-17-6-4-3-5-7-17)29-23(32)15-28-24(33)20(27)13-18-8-10-19(31)11-9-18/h3-11,16,20-22,31H,12-15,27H2,1-2H3,(H,28,33)(H,29,32)(H,30,34)(H,35,36)/t20-,21-,22-/m0/s1

InChIKey= JMEQPUQYEDILLR-FKBYEOEOSA-N


Opioid agonist according to the BIOPEP-UWM database of bioactive peptides (ID 3552)
Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 10101); the MBPDB database
Mucin secretion simulating peptide according to the BIOPEP-UWM database of bioactive peptides (10114); the MBPDB database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 501), the EROP-Moscow database


Database reference:
AHTPDB: ID 1208, 1329, 1738, 1940, 2013, 2975, 3304, 3737, 4152, 4264, 4876, 4986, 6468

BIOPEP-UWM database of bioactive peptides: ID 3552; 10101; 10114

BIOPEP-UWM database of sensory peptides and amino acids: ID 501

ChemSpider: ID 57266718

EPA DSSTox: ID DTXSID60648407

EROP-Moscow: ID E23518

FeptideDB: ID 3552; 3554

J-GLOBAL: ID 200907091921113663

MBPDB: Peptide YGLF

Nikkaji: ID J1.319.303G

PubChem: CID 25005402

SATPdb: ID satpdb14733