BIOPEP-UWM: Report
ID | 3557 |
Name | ACE inhibitor |
sequence |
Function: | |||
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) | |||
Number of residues | 3 |
Activity code | ah |
Activity : | ACE inhibitor |
|||
Chemical mass | 407.4200 | Monoisotopic mass | 407.1799 | |
EC50 : | 335.00 µM |
Bibliographic data: | |
Authors | |
Yano S., Suzuki K., Funatsu G. | |
Title | |
Isolation from alpha-zein of thermolysin peptides with angiotensin I-converting enzyme inhibitory activity. Biosci. Biotech. Biochem., 60(4), 661-663 (1996) | |
Year | Source |
1996 | Journal |
Additional information: |
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(Cc1ccccc1)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(O)=O InChI=1S/C18H25N5O6/c19-11(8-10-4-2-1-3-5-10)16(26)23-13(9-15(21)25)17(27)22-12(18(28)29)6-7-14(20)24/h1-5,11-13H,6-9,19H2,(H2,20,24)(H2,21,25)(H,22,27)(H,23,26)(H,28,29)/t11-,12-,13-/m0/s1 InChIKey=MRNRMSDVVSKPGM-AVGNSLFASA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: XM02-00. Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
Database reference: |