BIOPEP-UWM: Report

ID 3580
Name ACE Inhibitor
sequence
DIGYY

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 629.6566 Monoisotopic mass 629.2687
IC50 :
3.39 µM



Bibliographic data:
Authors
Matsui T., Li C.-H., Osajima Y.
Title
Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ. J. Peptide Sci., 5, 289-297, 1999
Year Source
1999 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@H](CC)C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)O

InChI=1S/C30H39N5O10/c1-3-16(2)26(35-27(41)21(31)14-25(39)40)29(43)32-15-24(38)33-22(12-17-4-8-19(36)9-5-17)28(42)34-23(30(44)45)13-18-6-10-20(37)11-7-18/h4-11,16,21-23,26,36-37H,3,12-15,31H2,1-2H3,(H,32,43)(H,33,38)(H,34,42)(H,35,41)(H,39,40)(H,44,45)/t16-,21-,22-,23-,26-/m0/s1

InChIKey: SGFPDJDJSONUPO-JAEJYZBISA-N




Database reference:
AHTPDB: ID 2325

BioPepDB: ID biopep00132

BRENDA: Ligand Asp-Ile-Gly-Tyr-Tyr

EROP-Moscow: ID E04075

SATPdb: ID satpdb21790