BIOPEP-UWM: Report

ID 3582
Name ACE Inhibitor
sequence
YYAPFDGIL
Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1058.1799 Monoisotopic mass 1057.5103
IC50 :
83.00 µM


Bibliographic data:
Authors
Takayanagi T., Yokotsuka K.
Title
Angiotensin I converting enzyme-inhibitory peptides from wine. Am. J. Enol. Viticult., 50, 65-68, 1999
Year Source
1999 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](C)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CC(C)C)C(=O)O

InChI=1S/C53H71N9O14/c1-6-30(4)45(51(73)60-41(53(75)76)23-29(2)3)61-43(65)28-55-47(69)40(27-44(66)67)58-49(71)39(25-32-11-8-7-9-12-32)59-50(72)42-13-10-22-62(42)52(74)31(5)56-48(70)38(26-34-16-20-36(64)21-17-34)57-46(68)37(54)24-33-14-18-35(63)19-15-33/h7-9,11-12,14-21,29-31,37-42,45,63-64H,6,10,13,22-28,54H2,1-5H3,(H,55,69)(H,56,70)(H,57,68)(H,58,71)(H,59,72)(H,60,73)(H,61,65)(H,66,67)(H,75,76)/t30-,31-,37-,38-,39-,40-,41-,42-,45-/m0/s1

InChIKey: KXTNTVZHPOVOND-IGQOJWJDSA-N


Database reference:
AHTPDB: ID 1908, 2441, 4615

BioPepDB: ID biopep01647

BRENDA: Ligand Tyr-Tyr-Ala-Pro-Phe-Asp-Gly-Ile-Leu

EROP-Moscow: ID E09348

SATPdb: ID satpdb18554