BIOPEP-UWM: Report

ID 3797
Name
sequence
WWPKHK~

Function:
 
Number of residues
6
Activity code
op
Activity :
opioid
Chemical mass 880.0469 Monoisotopic mass 879.4855
EC50 :
0.01 µM



Bibliographic data:
Authors
Dooley C.T., Kaplan R.A., Chung N.N., Schiller P.W., Bidlack J.M., Houghten R.A.
Title
Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries. Peptide Research, 8, 3, 124-137(1995)
Year Source
1995 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](CCCCN)(NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]1([H])CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(N)=O

InChI=1S/C45H61N13O6/c46-17-7-5-14-35(40(49)59)54-43(62)37(22-29-25-50-26-53-29)56-42(61)36(15-6-8-18-47)55-44(63)39-16-9-19-58(39)45(64)38(21-28-24-52-34-13-4-2-11-31(28)34)57-41(60)32(48)20-27-23-51-33-12-3-1-10-30(27)33/h1-4,10-13,23-26,32,35-39,51-52H,5-9,14-22,46-48H2,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,61)(H,57,60)/t32-,35-,36-,37-,38-,39-/m0/s1

InChIKey=NTZAYICEUWRFAA-YKKUXQLDSA-N


Originally EC50 was expressed in [nM], in BIOPEP-UWM EC50 value was transformed to [uM].




Database reference: