BIOPEP-UWM: Report

ID 3911
Name citropin 1.1 from Australian frog
sequence
GLFDVIKKVASVIGGLG
Function:
Peptide derived from the secretion of the granular dorsal glands of the Green and Golden Bell Frog Litoria aurea. Peptides isolated from amphibians show wide-spectrum antibiotic and anticancer activity.
 
Number of residues
17
Activity code
ac
Activity :
anticancer
Chemical mass 1673.0000 Monoisotopic mass 1671.9892
EC50 :
0.00 µM


Bibliographic data:
Authors
Rozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.
Title
The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(CC)[C@]([H])(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(C)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CC(C)C)NC(=O)CN)C(C)C)[C@@]([H])(C)CC)C(C)C)C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O

InChI=1S/C78H133N19O21/c1-16-45(13)64(74(114)83-36-57(100)82-37-58(101)87-51(31-40(3)4)67(107)84-38-60(104)105)96-76(116)63(44(11)12)95-73(113)55(39-98)92-66(106)47(15)85-75(115)61(42(7)8)93-69(109)50(28-22-24-30-80)88-68(108)49(27-21-23-29-79)89-78(118)65(46(14)17-2)97-77(117)62(43(9)10)94-72(112)54(34-59(102)103)91-71(111)53(33-48-25-19-18-20-26-48)90-70(110)52(32-41(5)6)86-56(99)35-81/h18-20,25-26,40-47,49-55,61-65,98H,16-17,21-24,27-39,79-81H2,1-15H3,(H,82,100)(H,83,114)(H,84,107)(H,85,115)(H,86,99)(H,87,101)(H,88,108)(H,89,118)(H,90,110)(H,91,111)(H,92,106)(H,93,109)(H,94,112)(H,95,113)(H,96,116)(H,97,117)(H,102,103)(H,104,105)/t45-,46-,47-,49-,50-,51-,52-,53-,54-,55-,61-,62-,63-,64-,65-/m0/s1

InChIKey=GSVIUYBLXKWEGD-GCQBAMSOSA-N


Database reference: