BIOPEP-UWM: Report

ID 3912
Name uperin 3.6
sequence
GVIDAAKKVVNVLKNLF~
Function:
Peptide derived from the secretion of the granular dorsal glands of the Green and Golden Bell Frog Litoria aurea. Peptides isolated from amphibians show wide-spectrum antibiotic and anticancer activity.
 
Number of residues
17
Activity code
ac
Activity :
anticancer
Chemical mass 1827.2123 Monoisotopic mass 1826.1108
EC50 :
0.00 µM


Bibliographic data:
Authors
Rozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.
Title
The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(CC)[C@]([H])(NC(=O)[C@@]([H])(NC(=O)CN)C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(N)=O

InChI=1S/C85H147N23O21/c1-17-48(14)69(108-83(127)65(44(6)7)104-63(111)41-89)85(129)103-60(40-64(112)113)76(120)94-49(15)71(115)93-50(16)72(116)95-52(29-21-24-32-86)73(117)96-54(31-23-26-34-88)75(119)105-68(47(12)13)84(128)107-67(46(10)11)82(126)102-59(39-62(91)110)80(124)106-66(45(8)9)81(125)101-57(36-43(4)5)77(121)97-53(30-22-25-33-87)74(118)100-58(38-61(90)109)79(123)99-56(35-42(2)3)78(122)98-55(70(92)114)37-51-27-19-18-20-28-51/h18-20,27-28,42-50,52-60,65-69H,17,21-26,29-41,86-89H2,1-16H3,(H2,90,109)(H2,91,110)(H2,92,114)(H,93,115)(H,94,120)(H,95,116)(H,96,117)(H,97,121)(H,98,122)(H,99,123)(H,100,118)(H,101,125)(H,102,126)(H,103,129)(H,104,111)(H,105,119)(H,106,124)(H,107,128)(H,108,127)(H,112,113)/t48-,49-,50-,52-,53-,54-,55-,56-,57-,58-,59-,60-,65-,66-,67-,68-,69-/m0/s1

InChIKey=JARHLUNZTMVLRU-RFRHLUBESA-N


Database reference: