BIOPEP-UWM: Report

ID 3913
Name uperin 3.6
sequence
GVIDAAKKVVNVLKNLFG
Function:
Peptide derived from the secretion of the granular dorsal glands of the Green and Golden Bell Frog Litoria aurea. Peptides isolated from amphibians show wide-spectrum antibiotic and anticancer activity.
 
Number of residues
18
Activity code
ac
Activity :
anticancer
Chemical mass 1885.2483 Monoisotopic mass 1884.1162
EC50 :
0.00 µM


Bibliographic data:
Authors
Rozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.
Title
The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(CC)[C@]([H])(NC(=O)[C@@]([H])(NC(=O)CN)C(C)C)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)NCC(O)=O

InChI=1S/C87H149N23O23/c1-17-49(14)71(110-85(131)67(45(6)7)106-64(113)41-91)87(133)105-61(40-65(114)115)78(124)96-50(15)72(118)95-51(16)73(119)97-53(29-21-24-32-88)75(121)98-55(31-23-26-34-90)77(123)107-70(48(12)13)86(132)109-69(47(10)11)84(130)104-60(39-63(93)112)82(128)108-68(46(8)9)83(129)103-57(36-44(4)5)79(125)99-54(30-22-25-33-89)76(122)102-59(38-62(92)111)81(127)100-56(35-43(2)3)80(126)101-58(74(120)94-42-66(116)117)37-52-27-19-18-20-28-52/h18-20,27-28,43-51,53-61,67-71H,17,21-26,29-42,88-91H2,1-16H3,(H2,92,111)(H2,93,112)(H,94,120)(H,95,118)(H,96,124)(H,97,119)(H,98,121)(H,99,125)(H,100,127)(H,101,126)(H,102,122)(H,103,129)(H,104,130)(H,105,133)(H,106,113)(H,107,123)(H,108,128)(H,109,132)(H,110,131)(H,114,115)(H,116,117)/t49-,50-,51-,53-,54-,55-,56-,57-,58-,59-,60-,61-,67-,68-,69-,70-,71-/m0/s1

InChIKey=KDQRVOULQULXMW-VGGYRCCTSA-N


Database reference: