BIOPEP-UWM: Report

ID 4005
Name Ubiquitin-mediated proteolysis activating peptide
sequence
RA
Function:
Activation of ubiquitin-dependent proteolysis
 
Number of residues
2
Activity code
apr
Activity :
activating ubiquitin-mediated proteolysis
Chemical mass 245.2781 Monoisotopic mass 245.1484
EC50 :
0.00 µM


Bibliographic data:
Authors
Turner G. C., Du F., Varshavsky A.
Title
Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature, 405, 579-582, 2000
Year Source
2000 Journal


Additional information:
BIOPEP database of bioactive peptides


SMILES: N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C9H19N5O3/c1-5(8(16)17)14-7(15)6(10)3-2-4-13-9(11)12/h5-6H,2-4,10H2,1H3,(H,14,15)(H,16,17)(H4,11,12,13)/t5-,6-/m0/s1

InChIKey: WVRUNFYJIHNFKD-WDSKDSINSA-N


Peptide inhibiting UBR protein according to the ChEMBL database; the PubChem database
Inhibitor of Leucyltransferase (EC 2.3.2.6) according to the BRENDA database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP database of bioactive peptides (ID 7588); the BRENDA database; the ChEMBL database; the PubChem database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP database of bioactive peptides (ID 8526)
Inhibitor of Bleomycin hydrolase (EC 3.4.22.40) (MEROPS ID: C01.084) according to the BRENDA database

Salty taste enhancing peptide according to the BIOPEP database of sensory peptides and amino acids (ID 420)


Database reference:
AHTPDB: ID 1679; 2999, 3182; 3227; 3531; 3582; 3830; 4018; 4432; 4536; 4678; 6574

BindingDB: ID 50407418

BIOPEP database of bioactive peptides: ID 7588; 8526

BIOPEP database of sensory peptides and amino acids: ID 420

BRENDA: Ligand Arg-Ala

ChEBI: ID 73810

ChEMBL: ID CHEMBL328471

ChemSpider: ID 5383289

PubChem: ID 7020333

SATPdb: ID satpdb10016

ZINC: ID ZINC02562523