BIOPEP-UWM: Report

ID 4006
Name Ubiquitin-mediated proteolysis activating peptide
sequence
LA
Function:
Activator of ubiquitin-mediated proteolysis
 
Number of residues
2
Activity code
apr
Activity :
activating ubiquitin-mediated proteolysis
Chemical mass 202.2501 Monoisotopic mass 202.1313
EC50 :
0.00 µM


Bibliographic data:
Authors
Turner G. C., Du F. Y., Varshavsky A.
Title
Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature, 405, 579-582, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)O)C)CC(C)C

InChI=1S/C9H18N2O3/c1-5(2)4-7(10)8(12)11-6(3)9(13)14/h5-7H,4,10H2,1-3H3,(H,11,12)(H,13,14)/t6-,7-/m0/s1

InChIKey: HSQGMTRYSIHDAC-BQBZGAKWSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 3175); the BRENDA database; the EROP-Moscow database
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database, the BindingDB database, the BIOPEP database of bioactive peptides (ID 7585)
Inhibitor of Bleomycin hydrolase (EC 3.4.22.40) (MEROPS ID: C01.084) according to the BRENDA database
Inhibitor of citrulline uptake in yeasts according to the ChEMBL database; the PubChem database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9499)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; the ChEMBL database; the PubChem database


Database reference:
ACToR: ID 21369-94-8

AHTPDB: ID 3224, 3308, 3513, 3569, 3595, 3828, 3852, 3973, 4437, 4534, 4672, 6571

BindingDB: ID 50407466

BioPepDB: ID biopep00725

BIOPEP-UWM database of bioactive peptides: ID 3175; 7585; 9499

BIOPEP-UWM database of sensory peptides and amino acids: ID 466

BRENDA: Ligand Leu-Ala

ChEBI: ID 73527

ChemBank: ID KBio3_002789; SPBio_001517; Spectrum2_001499; Spectrum3_001934

ChEMBL: ID CHEMBL541207

ChemIDplus: ID 007298842

ChemSpider: ID 73739

EROP-Moscow: ID E06287

J-GLOBAL: ID 200907083420885213

Nikkaji: ID J81.361C

PubChem: ID 81721

SATPDB: ID satpdb13367

SureChEMBL: ID SCHEMBL259116

ZINC: ID ZINC01569727