BIOPEP-UWM: Report

ID 4007
Name Peptide activating ubiquitin-mediated proteolysis
sequence
WA
Function:
Activating ubiquitin-mediated proteolysis
 
Number of residues
2
Activity code
apr
Activity :
activating ubiquitin-mediated proteolysis
Chemical mass 275.3024 Monoisotopic mass 275.1266
EC50 :
0.00 µM


Bibliographic data:
Authors
Turner G. C., Du F., Varshavsky A.
Title
Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway. Nature, 405, 579-582, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)N[C@@H](C)C(=O)O

InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1

InChIKey: OHGNSVACHBZKSS-KWQFWETISA-N


Peptide enhances its uptake in Saccharomyces cerevisiae.


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8528); the EROP-Moscow database
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9089)


Database reference:
AHTPDB: ID 1081, 1464, 2784, 4721, 5180, 6156

BindingDB: ID 50169160

BioPepDB: ID biopep01514

BIOPEP-UWM database of bioactive peptides: ID 8528; 9089

BRENDA: Ligand Trp-Ala

ChEBI: ID 73710

ChEMBL: ID CHEMBL188866

ChemSpider: ID 5361479

EROP-Moscow: ID E09197

J-GLOBAL: ID 200907006406167567

Metabolights: ID MTBLC73710

Nikkaji: ID J149.637I

PubChem: CID 6993401

SATPdb: ID satpdb14491

SureChEMBL: ID SCHEMBL1617917

ZINC: ID ZINC000001638007