BIOPEP-UWM: Report

ID 4008
Name ACE Inhibitor
sequence
GGVIPN

Function:
Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 555.6228 Monoisotopic mass 555.3007
IC50 :
0.74 µM



Bibliographic data:
Authors
Matsui T., Li C.-H., Osajima Y.
Title
Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ. J. Peptide Sci., 5, 289-297, 1999
Year Source
1999 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O

InChI=1S/C24H41N7O8/c1-5-13(4)20(30-22(36)19(12(2)3)29-18(34)11-27-17(33)10-25)23(37)31-8-6-7-15(31)21(35)28-14(24(38)39)9-16(26)32/h12-15,19-20H,5-11,25H2,1-4H3,(H2,26,32)(H,27,33)(H,28,35)(H,29,34)(H,30,36)(H,38,39)/t13-,14-,15-,19-,20-/m0/s1

InChIKey: LKNOHWMJXPKAHT-QEFISFJRSA-N




Database reference:
AHTPDB: ID 2303, 2866

BioPepDB: ID biopep00347

BRENDA: Ligand Gly-Gly-Val-Ile-Pro-Asn

EROP-Moscow: ID E09349

SATPdb: ID satpdb16934