BIOPEP-UWM: Report

ID 4017
Name Anticancer peptide
sequence
YK
Function:
Anticancer
 
Number of residues
2
Activity code
ac
Activity :
anticancer
Chemical mass 309.3599 Monoisotopic mass 309.1683
EC50 :
0.00 µM


Bibliographic data:
Authors
Otani H., Suzuki H.
Title
Isolation and characterization of cytotoxic small peptides, α-casecidins, from bovine αs1-casein digested with bovine trypsin. Anim. Sci. J., 74, 427–435, 2003
Year Source
2003 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C15H23N3O4/c16-8-2-1-3-13(15(21)22)18-14(20)12(17)9-10-4-6-11(19)7-5-10/h4-7,12-13,19H,1-3,8-9,16-17H2,(H,18,20)(H,21,22)/t12-,13-/m0/s1

InChIKey=AOLHUMAVONBBEZ-STQMWFEESA-N


Cytotoxic peptide according to the BIOPEP-UWM database of bioactive peptides (ID 4015)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02.001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID: 7697).
Inhibitor of Dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID:8939)
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) acording to the BIOPEP-UWM database of bioactive peptides (ID 9483)


Database reference:
AHTPDB: ID 1698, 2990, 3028, 3066, 3147, 3169, 3173, 3188, 3271, 3338, 3549, 6683

BioPepDB: ID biopep01573

BIOPEP-UWM database of bioactive peptides: ID 4015; 7697; 8939; 9483

CHEBI: ID CHEBI:75004

ChEMBL: ID CHEMBL1221518

ChemSpider: ID 5384727

J-GLOBAL: ID 200907074120119951

MBPDB: Peptide YK

Metabolights: ID MTBLC75004

MMsINC: ID MMs00484507

Nikkaji: ID J522.537J

PubChem: CID 7021830

SATPdb: ID satpdb27145

SureChEMBL: ID SCHEMBL338636

ZINC: ID ZINC2575131