BIOPEP-UWM: Report

ID 5318
Name Aurein 2.5 - antibacterial
sequence
GLFDIVKKVVGAFGSL~
Function:
Antibacterial
 
Number of residues
16
Activity code
ab
Activity :
antibacterial
Chemical mass 1648.9803 Monoisotopic mass 1647.9682
EC50 :
0.00 µM


Bibliographic data:
Authors
Rozek T., Wegener K., Bowie J., Olver I. N., Carver J. A., Wallace J. C., Tyler M. J.
Title
The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis. Eur. J. Biochem, 267, 5330-5341, 2000
Year Source
2000 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(CC)[C@]([H])(NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CC(C)C)NC(=O)CN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)NCC(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(N)=O

InChI=1S/C79H129N19O19/c1-14-47(12)66(98-74(112)57(37-62(103)104)94-73(111)56(36-50-27-19-16-20-28-50)93-72(110)54(34-43(4)5)87-59(100)38-82)79(117)97-64(45(8)9)77(115)90-51(29-21-23-31-80)70(108)89-52(30-22-24-32-81)71(109)95-65(46(10)11)78(116)96-63(44(6)7)76(114)85-39-60(101)86-48(13)68(106)92-55(35-49-25-17-15-18-26-49)69(107)84-40-61(102)88-58(41-99)75(113)91-53(67(83)105)33-42(2)3/h15-20,25-28,42-48,51-58,63-66,99H,14,21-24,29-41,80-82H2,1-13H3,(H2,83,105)(H,84,107)(H,85,114)(H,86,101)(H,87,100)(H,88,102)(H,89,108)(H,90,115)(H,91,113)(H,92,106)(H,93,110)(H,94,111)(H,95,109)(H,96,116)(H,97,117)(H,98,112)(H,103,104)/t47-,48-,51-,52-,53-,54-,55-,56-,57-,58-,63-,64-,65-,66-/m0/s1

InChIKey=IWQLCLFYFFHMGQ-XIFPNSEASA-N

Anticancer peptide according to the BIOPEP-UWM database of bioactive peptides (ID 7045)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 7045