BIOPEP-UWM: Report

ID 5344
Name Bacteriocin sakacin A
sequence
ARSYGNGVYCNNKKCWVNRGEATQSIIGGMISGWASGLAGM
Function:
Bactericidal activity; inhibits closely related Lactobacilli, Listeria monocytogenes and ivanovvi, Enterococcus faecalis, Carnobacterium sp. and Brocothrix thermosphacta.
 
Number of residues
41
Activity code
ab
Activity :
antibacterial
Chemical mass 4308.8500 Monoisotopic mass 4306.0228
EC50 :
0.00 µM


Bibliographic data:
Authors
Tichaczek P.S., Nissen-Meyer J., Nes I.F., Vogel R.F., Hammes W.P.;
Title
"Characterization of the bacteriocins curvacin A from Lactobacillus curvatus LTH1174 and sakacin P from L. sake LTH673."; Syst. Appl. Microbiol. 15:460-465(1992)
Year Source
1992 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@@](C)(N)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@]([H])(CC(N)=O)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@]([H])(C(=O)N[C@]([H])(C(=O)NCC(=O)NCC(=O)N[C@@]([H])(CCSC)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CCSC)C(O)=O)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)O

InChI=1S/C184H288N56O56S4/c1-20-89(10)146(176(289)208-72-135(253)201-73-136(254)213-113(53-59-299-18)164(277)237-147(90(11)21-2)179(292)232-125(81-242)158(271)207-78-140(258)216-118(64-99-70-199-105-35-25-23-33-103(99)105)166(279)211-94(15)152(265)229-124(80-241)157(270)206-77-139(257)215-115(61-86(4)5)165(278)209-93(14)151(264)202-74-138(256)214-114(182(295)296)54-60-300-19)239-180(293)148(91(12)22-3)238-173(286)127(83-244)231-163(276)112(49-51-130(188)248)222-181(294)149(96(17)245)240-153(266)95(16)210-159(272)111(50-52-143(261)262)212-137(255)75-203-154(267)107(39-31-57-197-183(193)194)219-169(282)123(69-134(192)252)228-178(291)145(88(8)9)236-171(284)119(65-100-71-200-106-36-26-24-34-104(100)106)224-174(287)128(84-297)233-162(275)109(38-28-30-56-186)220-160(273)108(37-27-29-55-185)221-168(281)121(67-132(190)250)225-170(283)122(68-133(191)251)226-175(288)129(85-298)234-167(280)117(63-98-43-47-102(247)48-44-98)227-177(290)144(87(6)7)235-142(260)79-205-156(269)120(66-131(189)249)217-141(259)76-204-155(268)116(62-97-41-45-101(246)46-42-97)223-172(285)126(82-243)230-161(274)110(218-150(263)92(13)187)40-32-58-198-184(195)196/h23-26,33-36,41-48,70-71,86-96,107-129,144-149,199-200,241-247,297-298H,20-22,27-32,37-40,49-69,72-85,185-187H2,1-19H3,(H2,188,248)(H2,189,249)(H2,190,250)(H2,191,251)(H2,192,252)(H,201,253)(H,202,264)(H,203,267)(H,204,268)(H,205,269)(H,206,270)(H,207,271)(H,208,289)(H,209,278)(H,210,272)(H,211,279)(H,212,255)(H,213,254)(H,214,256)(H,215,257)(H,216,258)(H,217,259)(H,218,263)(H,219,282)(H,220,273)(H,221,281)(H,222,294)(H,223,285)(H,224,287)(H,225,283)(H,226,288)(H,227,290)(H,228,291)(H,229,265)(H,230,274)(H,231,276)(H,232,292)(H,233,275)(H,234,280)(H,235,260)(H,236,284)(H,237,277)(H,238,286)(H,239,293)(H,240,266)(H,261,262)(H,295,296)(H4,193,194,197)(H4,195,196,198)/t89-,90-,91-,92-,93-,94-,95-,96+,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,144-,145-,146-,147-,148-,149-/m0/s1

InChIKey=UJEBRENGWBFEPI-BYOBOFJMSA-N


Database reference:
SWISS-PROT SAKA_LACSK