BIOPEP-UWM: Report

ID 5349
Name Acaloleptin A1
sequence
SLQPGAPNVNNKDQPWQVSPHISRDDSGNTRTDINVQRHGENNDFEAGWSKVVRGPNKAKPTWHIGGTHRW
Function:
Antibacterial activity against gram-negative bacteria but not against gram-positive bacteria
 
Number of residues
71
Activity code
ab
Activity :
antibacterial
Chemical mass 7994.5572 Monoisotopic mass 7989.9105
EC50 :
0.00 µM


Bibliographic data:
Authors
Mamura M., Wada S., Koizumi N., Kadotani T., Yaoi K., Sato R., Iwahana H.;
Title
"Acaloleptins A: inducible antibacterial peptides from larvae of the beetle, Acalolepta luxuriosa."; Arch. Insect Biochem. Physiol. 40:88-98.
Year Source
1999 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)CNC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@]([H])(NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CCCN1C(=O)CNC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@@]([H])(NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)[C@]([H])(C)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(N)=O)NC(=O)CNC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CO)NC(=O)[C@@]([H])(NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CO)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(C)NC(=O)CNC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CCC(N)=O)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@@]([H])(N)CO)C(C)C)C(C)C)[C@@]([H])(C)CC)[C@@]([H])(C)O)[C@@]([H])(C)O)[C@@]([H])(C)CC)C(C)C)C(C)C)C(C)C)[C@@]([H])(C)O)[C@@]([H])(C)CC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI=1S/C346H526N114O107/c1-26-164(16)271(324(549)392-142-252(482)387-143-257(487)443-274(170(22)466)332(557)434-213(118-180-139-375-155-395-180)300(525)407-198(76-51-103-381-345(370)371)289(514)438-229(341(566)567)116-178-137-386-191-68-39-35-64-186(178)191)449-310(535)214(119-181-140-376-156-396-181)421-299(524)211(115-177-136-385-190-67-38-34-63-185(177)190)433-335(560)277(173(25)469)454-323(548)239-83-58-109-459(239)337(562)204(72-43-47-99-350)415-279(504)168(20)400-284(509)193(69-40-44-96-347)405-302(527)220(125-248(360)478)431-319(544)235-79-53-105-455(235)258(488)148-393-281(506)192(73-48-100-378-342(364)365)412-326(551)269(162(12)13)448-329(554)270(163(14)15)445-292(517)195(71-42-46-98-349)408-316(541)231(151-463)440-297(522)209(113-175-134-383-188-65-36-32-61-183(175)188)402-255(485)145-388-278(503)167(19)399-285(510)203(89-95-260(491)492)411-296(521)208(112-174-59-30-29-31-60-174)419-307(532)226(131-263(497)498)427-304(529)219(124-247(359)477)424-303(528)218(123-246(358)476)422-290(515)200(88-94-259(489)490)401-254(484)146-389-282(507)212(117-179-138-374-154-394-179)420-287(512)196(74-49-101-379-343(366)367)404-291(516)201(84-90-240(352)470)414-325(550)266(159(6)7)446-314(539)223(128-251(363)481)436-330(555)272(165(17)27-2)451-315(540)228(133-265(501)502)437-334(559)276(172(24)468)452-293(518)199(77-52-104-382-346(372)373)413-333(558)275(171(23)467)453-312(537)216(121-244(356)474)403-256(486)147-390-283(508)230(150-462)439-309(534)227(132-264(499)500)428-308(533)225(130-262(495)496)426-288(513)197(75-50-102-380-344(368)369)409-317(542)232(152-464)441-331(556)273(166(18)28-3)450-311(536)215(120-182-141-377-157-397-182)430-322(547)238-82-57-110-460(238)340(565)233(153-465)442-328(553)268(161(10)11)444-294(519)202(85-91-241(353)471)410-298(523)210(114-176-135-384-189-66-37-33-62-184(176)189)429-321(546)237-81-56-108-458(237)339(564)206(87-93-243(355)473)417-306(531)224(129-261(493)494)425-286(511)194(70-41-45-97-348)406-301(526)217(122-245(357)475)423-305(530)221(126-249(361)479)435-327(552)267(160(8)9)447-313(538)222(127-250(362)480)432-320(545)236-80-55-106-456(236)336(561)169(21)398-253(483)144-391-318(543)234-78-54-107-457(234)338(563)205(86-92-242(354)472)416-295(520)207(111-158(4)5)418-280(505)187(351)149-461/h29-39,59-68,134-141,154-173,187,192-239,266-277,383-386,461-469H,26-28,40-58,69-133,142-153,347-351H2,1-25H3,(H2,352,470)(H2,353,471)(H2,354,472)(H2,355,473)(H2,356,474)(H2,357,475)(H2,358,476)(H2,359,477)(H2,360,478)(H2,361,479)(H2,362,480)(H2,363,481)(H,374,394)(H,375,395)(H,376,396)(H,377,397)(H,387,482)(H,388,503)(H,389,507)(H,390,508)(H,391,543)(H,392,549)(H,393,506)(H,398,483)(H,399,510)(H,400,509)(H,401,484)(H,402,485)(H,403,486)(H,404,516)(H,405,527)(H,406,526)(H,407,525)(H,408,541)(H,409,542)(H,410,523)(H,411,521)(H,412,551)(H,413,558)(H,414,550)(H,415,504)(H,416,520)(H,417,531)(H,418,505)(H,419,532)(H,420,512)(H,421,524)(H,422,515)(H,423,530)(H,424,528)(H,425,511)(H,426,513)(H,427,529)(H,428,533)(H,429,546)(H,430,547)(H,431,544)(H,432,545)(H,433,560)(H,434,557)(H,435,552)(H,436,555)(H,437,559)(H,438,514)(H,439,534)(H,440,522)(H,441,556)(H,442,553)(H,443,487)(H,444,519)(H,445,517)(H,446,539)(H,447,538)(H,448,554)(H,449,535)(H,450,536)(H,451,540)(H,452,518)(H,453,537)(H,454,548)(H,489,490)(H,491,492)(H,493,494)(H,495,496)(H,497,498)(H,499,500)(H,501,502)(H,566,567)(H4,364,365,378)(H4,366,367,379)(H4,368,369,380)(H4,370,371,381)(H4,372,373,382)/t164-,165-,166-,167-,168-,169-,170+,171+,172+,173+,187-,192-,193-,194-,195-,196-,197-,198-,199-,200-,201-,202-,203-,204-,205-,206-,207-,208-,209-,210-,211-,212-,213-,214-,215-,216-,217-,218-,219-,220-,221-,222-,223-,224-,225-,226-,227-,228-,229-,230-,231-,232-,233-,234-,235-,236-,237-,238-,239-,266-,267-,268-,269-,270-,271-,272-,273-,274-,275-,276-,277-/m0/s1

InChIKey=AINXTARGHYSZQM-FJOKLHPDSA-N


Database reference:
SWISS-PROT ACA1_ACALU