BIOPEP-UWM: Report

ID 5354
Name Antimicrobial peptide CHP1
sequence
GRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIR
Function:
Bactericidal activity; inhibits Staphylococcus aureus and Escherichia coli.
 
Number of residues
39
Activity code
ab
Activity :
antibacterial
Chemical mass 4480.3956 Monoisotopic mass 4477.2694
EC50 :
0.00 µM


Bibliographic data:
Authors
Evans E.W., Beach G.G., Wunderlich J., Harmon B.G.;
Title
"Isolation of antimicrobial peptides from avian heterophils.";J. Leukoc. Biol. 56:661-665.
Year Source
1994 Journal


Additional information:
IOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CO)NC(=O)[C@]1([H])CCCN1C(=O)[C@]([H])(CS)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(C)NC(=O)[C@]([H])(CS)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)CNC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CS)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)CN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O)[C@@]([H])(C)CC)[C@@]([H])(C)CC

InChI=1S/C196H321N59O49S6/c1-15-107(11)153(187(299)231-126(191(303)304)62-43-77-217-196(211)212)252-167(279)125(61-42-76-216-195(209)210)226-161(273)119(54-30-35-69-198)230-182(294)143(98-306)250-185(297)146(101-309)248-169(281)128(80-104(5)6)234-173(285)135(87-115-64-66-116(262)67-65-115)237-174(286)134(86-114-51-27-20-28-52-114)236-163(275)124(60-41-75-215-194(207)208)229-178(290)139(94-258)243-184(296)145(100-308)246-160(272)117(53-29-34-68-197)222-150(264)90-218-158(270)138(93-257)245-188(300)154(108(12)16-2)253-176(288)130(82-106(9)10)240-189(301)155(110(14)261)254-177(289)129(81-105(7)8)235-180(292)141(96-260)244-186(298)148-63-44-78-255(148)190(302)147(102-310)251-166(278)122(57-33-38-72-201)227-168(280)127(79-103(3)4)233-172(284)132(84-112-47-23-18-24-48-112)232-156(268)109(13)220-181(293)142(97-305)247-170(282)131(83-111-45-21-17-22-46-111)223-151(265)91-219-157(269)137(92-256)241-164(276)120(55-31-36-70-199)225-162(274)123(59-40-74-214-193(205)206)228-171(283)133(85-113-49-25-19-26-50-113)238-183(295)144(99-307)249-175(287)136(88-152(266)267)239-179(291)140(95-259)242-165(277)121(56-32-37-71-200)224-159(271)118(221-149(263)89-202)58-39-73-213-192(203)204/h17-28,45-52,64-67,103-110,117-148,153-155,256-262,305-310H,15-16,29-44,53-63,68-102,197-202H2,1-14H3,(H,218,270)(H,219,269)(H,220,293)(H,221,263)(H,222,264)(H,223,265)(H,224,271)(H,225,274)(H,226,273)(H,227,280)(H,228,283)(H,229,290)(H,230,294)(H,231,299)(H,232,268)(H,233,284)(H,234,285)(H,235,292)(H,236,275)(H,237,286)(H,238,295)(H,239,291)(H,240,301)(H,241,276)(H,242,277)(H,243,296)(H,244,298)(H,245,300)(H,246,272)(H,247,282)(H,248,281)(H,249,287)(H,250,297)(H,251,278)(H,252,279)(H,253,288)(H,254,289)(H,266,267)(H,303,304)(H4,203,204,213)(H4,205,206,214)(H4,207,208,215)(H4,209,210,216)(H4,211,212,217)/t107-,108-,109-,110+,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,153-,154-,155-/m0/s1

InChIKey=UNTDRBIJJLBSEF-OPVKNATOSA-N


Database reference:
SWISS-PROT AMP1_CHICK