BIOPEP-UWM: Report

ID 5359
Name Myeloid antibacterial peptide 37(PMAP37 )
sequence
GLLSRLRDFLSDRGRRLGEKIERIGQKIKDLSEFFQS
Function:
Exerts antimicrobial activity against both gram-positive and negative bacteria with minimal inhibitory concentrations
 
Number of residues
37
Activity code
ab
Activity :
antibacterial
Chemical mass 4364.9508 Monoisotopic mass 4362.3964
EC50 :
0.00 µM


Bibliographic data:
Authors
Tossi A., Scocchi M., Zanetti M., Storici P., Gennaro R.;
Title
"PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity."; Eur. J. Biochem. 228:941-946
Year Source
1995 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(CC)[C@]([H])(NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)CNC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)CNC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(Cc1ccccc1)NC(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CO)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@]([H])(CC(C)C)NC(=O)CN)[C@@]([H])(C)CC)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(O)=O)[C@@]([H])(C)CC

InChI=1S/C192H320N60O56/c1-19-103(16)151(183(304)219-92-144(262)221-118(58-63-139(197)257)161(282)225-112(50-32-35-69-194)166(287)251-152(104(17)20-2)184(305)233-111(49-31-34-68-193)157(278)243-133(87-149(271)272)178(299)239-128(82-102(14)15)173(294)247-136(94-254)181(302)232-121(61-66-146(265)266)164(285)240-130(84-107-45-27-23-28-46-107)176(297)241-129(83-106-43-25-22-26-44-106)174(295)231-120(59-64-140(198)258)165(286)249-138(96-256)186(307)308)250-168(289)117(57-42-76-216-192(209)210)228-163(284)122(62-67-147(267)268)234-185(306)153(105(18)21-3)252-167(288)113(51-33-36-70-195)226-162(283)119(60-65-145(263)264)222-143(261)91-218-155(276)123(77-97(4)5)235-158(279)114(54-39-73-213-189(203)204)227-156(277)110(53-38-72-212-188(201)202)220-142(260)90-217-154(275)109(52-37-71-211-187(199)200)224-177(298)132(86-148(269)270)245-182(303)137(95-255)248-172(293)127(81-101(12)13)238-175(296)131(85-108-47-29-24-30-48-108)242-179(300)134(88-150(273)274)244-160(281)115(55-40-74-214-190(205)206)229-170(291)125(79-99(8)9)236-159(280)116(56-41-75-215-191(207)208)230-180(301)135(93-253)246-171(292)126(80-100(10)11)237-169(290)124(78-98(6)7)223-141(259)89-196/h22-30,43-48,97-105,109-138,151-153,253-256H,19-21,31-42,49-96,193-196H2,1-18H3,(H2,197,257)(H2,198,258)(H,217,275)(H,218,276)(H,219,304)(H,220,260)(H,221,262)(H,222,261)(H,223,259)(H,224,298)(H,225,282)(H,226,283)(H,227,277)(H,228,284)(H,229,291)(H,230,301)(H,231,295)(H,232,302)(H,233,305)(H,234,306)(H,235,279)(H,236,280)(H,237,290)(H,238,296)(H,239,299)(H,240,285)(H,241,297)(H,242,300)(H,243,278)(H,244,281)(H,245,303)(H,246,292)(H,247,294)(H,248,293)(H,249,286)(H,250,289)(H,251,287)(H,252,288)(H,263,264)(H,265,266)(H,267,268)(H,269,270)(H,271,272)(H,273,274)(H,307,308)(H4,199,200,211)(H4,201,202,212)(H4,203,204,213)(H4,205,206,214)(H4,207,208,215)(H4,209,210,216)/t103-,104-,105-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,151-,152-,153-/m0/s1

InChIKey=BYRQHCNIBNQSAE-WYRLYINZSA-N


Database reference:
SWISS-PROT ENTRY OF PREPROPEPTIDE: MP37_PIG