BIOPEP-UWM: Report

ID 5360
Name cecropin1 (Ceratitis capitata)
sequence
GWLKKIGKKIERVGQHTRDATIQTIAVAQQAANVAATARG
Function:
Cecropins have lytic and antibacterial activity against several gram-positive and gram-negative bacteria.
 
Number of residues
40
Activity code
ab
Activity :
antibacterial
Chemical mass 4257.8443 Monoisotopic mass 4255.3707
EC50 :
0.00 µM


Bibliographic data:
Authors
Andra J., Berninghausen., Leippe M.,
Title
Cecropins, antibacterial peptides from insects and mammals, are potently fungicidal against Candida Albicans. Med. Microbiol. Immunol. 189: 169-173
Year Source
2001 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](C)(O)[C@]([H])(NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@]([H])(CCC(N)=O)NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCNC(N)=N)NC(=O)[C@]([H])(CCC(O)=O)NC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCCN)NC(=O)CNC(=O)[C@@]([H])(NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CCCCN)NC(=O)[C@]([H])(CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@]([H])(C)CC)[C@@]([H])(C)CC)C(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@]([H])(C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)NCC(O)=O)[C@@]([H])(C)O)[C@@]([H])(C)CC)[C@@]([H])(C)O)[C@@]([H])(C)CC)[C@@]([H])(C)O

InChI=1S/C185H315N61O54/c1-29-88(13)139(239-164(282)111(50-37-41-67-188)225-158(276)110(49-36-40-66-187)227-168(286)120(72-84(5)6)233-169(287)121(221-130(256)77-190)73-104-78-206-107-47-34-33-46-106(104)107)173(291)208-81-131(257)219-109(48-35-39-65-186)157(275)224-112(51-38-42-68-189)165(283)240-141(90(15)31-3)177(295)231-119(59-64-133(259)260)162(280)226-114(54-45-71-205-185(200)201)163(281)237-136(85(7)8)172(290)207-80-132(258)220-115(55-60-125(191)251)160(278)234-122(74-105-79-202-83-210-105)170(288)246-144(101(26)248)180(298)229-113(53-44-70-204-184(198)199)159(277)235-124(76-134(261)262)167(285)214-98(23)154(272)244-145(102(27)249)181(299)242-142(91(16)32-4)178(296)230-118(58-63-128(194)254)166(284)245-146(103(28)250)182(300)241-140(89(14)30-2)176(294)217-99(24)152(270)236-137(86(9)10)174(292)216-95(20)150(268)223-117(57-62-127(193)253)161(279)228-116(56-61-126(192)252)156(274)213-92(17)147(265)211-94(19)151(269)232-123(75-129(195)255)171(289)238-138(87(11)12)175(293)215-93(18)148(266)212-97(22)153(271)243-143(100(25)247)179(297)218-96(21)149(267)222-108(52-43-69-203-183(196)197)155(273)209-82-135(263)264/h33-34,46-47,78-79,83-103,108-124,136-146,206,247-250H,29-32,35-45,48-77,80-82,186-190H2,1-28H3,(H2,191,251)(H2,192,252)(H2,193,253)(H2,194,254)(H2,195,255)(H,202,210)(H,207,290)(H,208,291)(H,209,273)(H,211,265)(H,212,266)(H,213,274)(H,214,285)(H,215,293)(H,216,292)(H,217,294)(H,218,297)(H,219,257)(H,220,258)(H,221,256)(H,222,267)(H,223,268)(H,224,275)(H,225,276)(H,226,280)(H,227,286)(H,228,279)(H,229,298)(H,230,296)(H,231,295)(H,232,269)(H,233,287)(H,234,278)(H,235,277)(H,236,270)(H,237,281)(H,238,289)(H,239,282)(H,240,283)(H,241,300)(H,242,299)(H,243,271)(H,244,272)(H,245,284)(H,246,288)(H,259,260)(H,261,262)(H,263,264)(H4,196,197,203)(H4,198,199,204)(H4,200,201,205)/t88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100+,101+,102+,103+,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-/m0/s1

InChIKey=FLXWVDKBIQQZAV-IOZRUUSCSA-N


Database reference:
SWISS-PROT ENTRY OF PREPORPEPTIDE: CEC1_CERCA