BIOPEP-UWM: Report

ID 5363
Name Antibacterial peptide CM-IV
sequence
RWKIFKKIEKVGQNIRDGIVKAGPAVAVVGQAATIG
Function:
Cecropins have lytic and antibacterial activity against several gram-positive and gram-negative bacteria.
 
Number of residues
36
Activity code
ab
Activity :
antibacterial
Chemical mass 3819.4912 Monoisotopic mass 3817.2140
EC50 :
0.00 µM


Bibliographic data:
Authors
Andra J., Berninghausen., Leippe M.,
Title
Cecropins, antibacterial peptides from insects and mammals, are potently fungicidal against Candida Albicans. Med. Microbiol. Immunol. 189: 169-173
Year Source
2001 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)NCC(=O)N[C@]([H])(C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@]([H])(C(=O)NCC(O)=O)[C@@]([H])(C)CC)[C@@]([H])(C)O)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC

InChI=1S/C174H293N51O45/c1-27-91(16)136(164(262)195-85-130(238)239)223-172(270)141(101(26)226)224-146(244)98(23)196-143(241)97(22)198-150(248)113(62-65-121(181)227)201-124(230)81-193-163(261)132(87(8)9)218-167(265)135(90(14)15)216-145(243)100(25)200-165(263)133(88(10)11)215-144(242)99(24)199-161(259)120-61-49-75-225(120)127(233)84-194-142(240)96(21)197-149(247)107(55-37-42-68-175)207-166(264)134(89(12)13)219-171(269)137(92(17)28-2)214-126(232)83-191-148(246)119(79-129(236)237)212-152(250)112(60-48-74-189-174(186)187)208-168(266)139(94(19)30-4)222-160(258)118(78-123(183)229)211-153(251)114(63-66-122(182)228)202-125(231)82-192-162(260)131(86(6)7)217-155(253)109(57-39-44-70-177)204-154(252)115(64-67-128(234)235)209-169(267)138(93(18)29-3)220-156(254)110(58-40-45-71-178)203-151(249)108(56-38-43-69-176)205-158(256)116(76-102-50-33-32-34-51-102)213-170(268)140(95(20)31-5)221-157(255)111(59-41-46-72-179)206-159(257)117(77-103-80-190-106-54-36-35-52-104(103)106)210-147(245)105(180)53-47-73-188-173(184)185/h32-36,50-52,54,80,86-101,105,107-120,131-141,190,226H,27-31,37-49,53,55-79,81-85,175-180H2,1-26H3,(H2,181,227)(H2,182,228)(H2,183,229)(H,191,246)(H,192,260)(H,193,261)(H,194,240)(H,195,262)(H,196,241)(H,197,247)(H,198,248)(H,199,259)(H,200,263)(H,201,230)(H,202,231)(H,203,249)(H,204,252)(H,205,256)(H,206,257)(H,207,264)(H,208,266)(H,209,267)(H,210,245)(H,211,251)(H,212,250)(H,213,268)(H,214,232)(H,215,242)(H,216,243)(H,217,253)(H,218,265)(H,219,269)(H,220,254)(H,221,255)(H,222,258)(H,223,270)(H,224,244)(H,234,235)(H,236,237)(H,238,239)(H4,184,185,188)(H4,186,187,189)/t91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101+,105-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-/m0/s1

InChIKey=UVQNAGIJXAWTJQ-GWJPOOFPSA-N


Database reference:
SWISS-PROT: CEC4_BOMMO