BIOPEP-UWM: Report

ID 5364
Name Cecropin A
sequence
RWKLFKKIEKVGRNVRDGLIKAGPAIAVIGQAKSLG
Function:
Cecropins have lytic and antibacterial activity against several gram-positive and gram-negative bacteria.
 
Number of residues
36
Activity code
ab
Activity :
antibacterial
Chemical mass 3918.6681 Monoisotopic mass 3916.3298
EC50 :
0.00 µM


Bibliographic data:
Authors
Yamano Y., Matsumoto M., Inoue K., Kawabata T., Morishima I.;
Title
"Cloning of cDNAs for cecropins A and B, and expression of the genes in the silkworm, Bombyx mori."; Biosci. Biotechnol. Biochem. 58:1476-1478.
Year Source
1994 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CC(O)=O)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@]([H])(C(=O)NCC(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(O)=O)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC)[C@@]([H])(C)CC

InChI=1S/C179H306N54O44/c1-25-98(17)142(171(272)201-88-133(238)209-119(64-66-130(187)235)154(255)205-103(22)147(248)211-113(56-35-41-69-181)159(260)225-128(91-234)168(269)220-121(78-92(5)6)151(252)203-90-138(245)246)232-173(274)141(97(15)16)226-148(249)105(24)207-174(275)143(99(18)26-2)229-149(250)104(23)206-169(270)129-63-49-77-233(129)135(240)89-202-146(247)102(21)204-153(254)112(55-34-40-68-180)217-175(276)145(101(20)28-4)231-166(267)122(79-93(7)8)210-134(239)86-199-152(253)127(84-137(243)244)224-158(259)118(62-48-76-197-179(193)194)216-172(273)140(96(13)14)228-167(268)126(83-131(188)236)223-155(256)111(61-47-75-196-178(191)192)208-132(237)87-200-170(271)139(95(11)12)227-161(262)116(59-38-44-72-184)213-160(261)120(65-67-136(241)242)218-176(277)144(100(19)27-3)230-162(263)117(60-39-45-73-185)212-156(257)114(57-36-42-70-182)214-164(265)124(81-106-50-30-29-31-51-106)222-163(264)123(80-94(9)10)221-157(258)115(58-37-43-71-183)215-165(266)125(82-107-85-198-110-54-33-32-52-108(107)110)219-150(251)109(186)53-46-74-195-177(189)190/h29-33,50-52,54,85,92-105,109,111-129,139-145,198,234H,25-28,34-49,53,55-84,86-91,180-186H2,1-24H3,(H2,187,235)(H2,188,236)(H,199,253)(H,200,271)(H,201,272)(H,202,247)(H,203,252)(H,204,254)(H,205,255)(H,206,270)(H,207,275)(H,208,237)(H,209,238)(H,210,239)(H,211,248)(H,212,257)(H,213,261)(H,214,265)(H,215,266)(H,216,273)(H,217,276)(H,218,277)(H,219,251)(H,220,269)(H,221,258)(H,222,264)(H,223,256)(H,224,259)(H,225,260)(H,226,249)(H,227,262)(H,228,268)(H,229,250)(H,230,263)(H,231,267)(H,232,274)(H,241,242)(H,243,244)(H,245,246)(H4,189,190,195)(H4,191,192,196)(H4,193,194,197)/t98-,99-,100-,101-,102-,103-,104-,105-,109-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,139-,140-,141-,142-,143-,144-,145-/m0/s1

InChIKey=BIDTUVAWYTZNFJ-ZOTFMDTBSA-N


Database reference:
SWISS-PROT ENTRY OF PREPROPEPTIDE: CECA_BOMMO